Subject: File No. SR-NASDAQ-2006-040
From: Christopher S Keenan
Affiliation: Director Investor Relations Cytokinetics

December 11, 2006

Sir/ Madam:

I believe that NASDAQs proposal will enhance competition in the market which is better for Cytokinetics and its investors. I use NASDAQ Online on a daily basis, it is a very valuable tool that is provided to us by our listing and it is a key part to performing our Investor Relations business practices.

Chris Keenan