Baker Bros. Advisors (GP) LLC (0001580575)

State location: NY | State of Inc.: DE | Fiscal Year End: 1231 Business Address 860 WASHINGTON STREET 3RD FLOOR NEW YORK NY 10014 (212)339-5600 Mailing Address 860 WASHINGTON STREET 3RD FLOOR NEW YORK NY 10014 Ownership Reports for Issuers: (Click on issuer name to see other owners for the issuer, or CIK for issuer filings.) Issuer Filings Transaction Date Type of Owner Replimune Group, Inc. 0001737953 2025-03-05 director, 10 percent owner SERA PROGNOSTICS, INC. 0001534969 2025-02-12 10 percent owner Kala Pharmaceuticals, Inc. Current Name:KALA BIO, Inc. 0001479419 2024-06-28 10 percent owner Kodiak Sciences Inc. 0001468748 2024-06-28 director, 10 percent owner Entrada Therapeutics, Inc. 0001689375 2024-06-25 10 percent owner MADRIGAL PHARMACEUTICALS, INC. Current Name:Entrada Therapeutics, Inc. 0001157601 2024-06-25 director Prelude Therapeutics Inc 0001678660 2024-06-14 director, 10 percent owner BeiGene, Ltd. 0001651308 2024-06-05 director, 10 percent owner Kiniksa Pharmaceuticals, Ltd. Current Name:Kiniksa Pharmaceuticals International, plc 0001730430 2024-06-05 director ACADIA PHARMACEUTICALS INC 0001070494 2024-05-29 director, 10 percent owner Immunocore Holdings plc 0001671927 2024-05-28 director TScan Therapeutics, Inc. 0001783328 2024-04-19 director BICYCLE THERAPEUTICS plc 0001761612 2024-04-18 director, 10 percent owner Kymera Therapeutics, Inc. 0001815442 2024-03-28 director vTv Therapeutics Inc. 0001641489 2024-02-27 director INCYTE CORP 0000879169 2023-12-29 director, 10 percent owner IGM Biosciences, Inc. 0001496323 2023-12-13 director, 10 percent owner Atreca, Inc. 0001532346 2023-10-19 other: Former 10% Owner DBV Technologies S.A. 0001613780 2022-06-13 director, 10 percent owner Talis Biomedical Corp 0001584751 2022-06-10 director, 10 percent owner Aeglea BioTherapeutics, Inc. Current Name:Spyre Therapeutics, Inc. 0001636282 2021-02-23 director SEATTLE GENETICS INC /WA Current Name:Seagen Inc. 0001060736 2020-12-31 director, 10 percent owner Zymeworks Inc. Current Name:Zymeworks BC Inc. 0001403752 2020-03-16 director HOOKIPA Pharma Inc. 0001760542 2019-04-17 10 percent owner Principia Biopharma Inc. 0001510487 2018-09-13 10 percent owner RHYTHM PHARMACEUTICALS, INC. 0001649904 2017-10-04 10 percent owner Intellia Therapeutics, Inc. 0001652130 2016-05-05 10 percent owner BELLICUM PHARMACEUTICALS, INC 0001358403 2015-12-24 10 percent owner Invitae Corp Current Name:InVitae Corp 0001501134 2015-08-27 10 percent owner Neoleukin Therapeutics, Inc. Current Name:Neurogene Inc. 0001404644 2015-08-07 10 percent owner ALEXION PHARMACEUTICALS INC Current Name:ALEXION PHARMACEUTICALS, INC. 0000899866 2015-06-22 director IDERA PHARMACEUTICALS, INC. Current Name:Aceragen, Inc. 0000861838 2014-03-10 director Mirati Therapeutics, Inc. 0001576263 2013-07-09 10 percent owner GENOMIC HEALTH INC 0001131324 2013-07-01 director, 10 percent owner XOMA Corp Current Name:XOMA Royalty Corp 0000791908 2013-07-01 director, 10 percent owner TRIMERIS INC Current Name:SYNAGEVA BIOPHARMA CORP 0000911326 2013-07-01 director, 10 percent owner BIOCRYST PHARMACEUTICALS INC 0000882796 2013-07-01 10 percent owner

Items 1 - 7

The information presented below contains only portions of the information presented in the referenced filing or filings.
You should consult the original filing for complete information. Hyperlinks to the forms are provided for your convenience.

Acquistion or Disposition	Transaction Date	Deemed Execution Date	Issuer	Form	Transaction Type	Direct or Indirect Ownership	Number of Securities Transacted	Number of Securities Owned	Line Number	Issuer CIK	Security Name
-	-		GENOMIC HEALTH INC	3	-	---			1	-	-
-	-		XOMA Corp	3	-	---			1	-	-
-	-		SYNAGEVA BIOPHARMA CORP	3	-	---			1	-	-
-	-		SEATTLE GENETICS INC /WA	3	-	---			1	-	-
-	-		INCYTE CORP	3	-	---			1	-	-
-	-		BIOCRYST PHARMACEUTICALS INC	3	-	---			1	-	-
-	-		ACADIA PHARMACEUTICALS INC	3	-	---			1	-	-

http://www.sec.gov/cgi-bin/own-disp

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