MCNEIL JOHN A (0001181558)

State location: CA | State of Inc.: DE | Fiscal Year End: 1231 Business Address 2292 FARADAY AVENUE CARLSBAD CA 92008 7609319200 Ownership Reports for Issuers: (Click on issuer name to see other owners for the issuer, or CIK for issuer filings.) Issuer Filings Transaction Date Type of Owner ISIS PHARMACEUTICALS INC Current Name:IONIS PHARMACEUTICALS INC 0000874015 2004-01-01 officer: VP, Infomatics

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You should consult the original filing for complete information. Hyperlinks to the forms are provided for your convenience.

Acquistion or Disposition	Transaction Date	Deemed Execution Date	Issuer	Form	Transaction Type	Direct or Indirect Ownership	Number of Securities Transacted	Number of Securities Owned	Line Number	Issuer CIK	Security Name
A	2005-01-03	2005-01-03	ISIS PHARMACEUTICALS INC	4	A-Award	--D	18158.0000	18158.0000	1	0000874015	Employee Stock Option (right to buy)
A	2004-01-02	2004-01-02	ISIS PHARMACEUTICALS INC	4	A-Award	--D	25000.0000	25000.0000	1	0000874015	Employee Stock Option (right to buy)

http://www.sec.gov/cgi-bin/own-disp

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