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U.S. Securities and Exchange Commission


BAKER JULIAN (0001087939)
Mailing Address
BAKER BROS. ADVISORS LP
860 WASHINGTON STREET 3RD FLOOR
NEW YORK NY 10014
Ownership Reports for Issuers: (Click on issuer name to see other owners for the issuer, or CIK for issuer filings.)

Issuer Filings Transaction Date Type of Owner
Replimune Group, Inc. 0001737953 2025-03-05 director, 10 percent owner
SERA PROGNOSTICS, INC. 0001534969 2025-02-12 10 percent owner
Kala Pharmaceuticals, Inc.
Current Name:KALA BIO, Inc.		 0001479419 2024-06-28 10 percent owner
Kodiak Sciences Inc. 0001468748 2024-06-28 director, 10 percent owner
Entrada Therapeutics, Inc. 0001689375 2024-06-25 10 percent owner
MADRIGAL PHARMACEUTICALS, INC.
Current Name:Entrada Therapeutics, Inc.		 0001157601 2024-06-25 director
Prelude Therapeutics Inc 0001678660 2024-06-14 director, 10 percent owner
BeiGene, Ltd. 0001651308 2024-06-05 director, 10 percent owner
Kiniksa Pharmaceuticals, Ltd.
Current Name:Kiniksa Pharmaceuticals International, plc		 0001730430 2024-06-05 director
ACADIA PHARMACEUTICALS INC 0001070494 2024-05-29 director, 10 percent owner
Immunocore Holdings plc 0001671927 2024-05-28 director
TScan Therapeutics, Inc. 0001783328 2024-04-19 director
BICYCLE THERAPEUTICS plc 0001761612 2024-04-18 director, 10 percent owner
Kymera Therapeutics, Inc. 0001815442 2024-03-28 director
vTv Therapeutics Inc. 0001641489 2024-02-27 director
INCYTE CORP 0000879169 2023-12-29 director, 10 percent owner
IGM Biosciences, Inc. 0001496323 2023-12-13 director, 10 percent owner
Atreca, Inc. 0001532346 2023-10-19 other: Former 10% Owner
DBV Technologies S.A. 0001613780 2022-06-13 director, 10 percent owner
Talis Biomedical Corp 0001584751 2022-06-10 director, 10 percent owner
Aeglea BioTherapeutics, Inc.
Current Name:Spyre Therapeutics, Inc.		 0001636282 2021-02-23 director
SEATTLE GENETICS INC /WA
Current Name:Seagen Inc.		 0001060736 2020-12-31 director, 10 percent owner
Zymeworks Inc.
Current Name:Zymeworks BC Inc.		 0001403752 2020-03-16 director
HOOKIPA Pharma Inc. 0001760542 2019-04-17 10 percent owner
Principia Biopharma Inc. 0001510487 2018-09-13 10 percent owner
RHYTHM PHARMACEUTICALS, INC. 0001649904 2017-10-04 10 percent owner
Intellia Therapeutics, Inc. 0001652130 2016-05-05 10 percent owner
BELLICUM PHARMACEUTICALS, INC 0001358403 2015-12-24 10 percent owner
Invitae Corp
Current Name:InVitae Corp		 0001501134 2015-08-27 10 percent owner
Neoleukin Therapeutics, Inc.
Current Name:Neurogene Inc.		 0001404644 2015-08-07 10 percent owner
ALEXION PHARMACEUTICALS INC
Current Name:ALEXION PHARMACEUTICALS, INC.		 0000899866 2015-06-22 director
Mirati Therapeutics, Inc. 0001576263 2013-07-09 10 percent owner
Ocera Therapeutics, Inc. 0001274644 2012-03-12 10 percent owner
XOMA Corp
Current Name:XOMA Royalty Corp		 0000791908 2012-03-06 10 percent owner
PHARMACYCLICS INC 0000949699 2011-08-22 10 percent owner
VAXGEN INC
Current Name:diaDexus, Inc.		 0001036968 2010-07-28 10 percent owner
ADOLOR CORP 0001076167 2010-04-23 10 percent owner
AUXILIUM PHARMACEUTICALS INC 0001182129 2010-03-09 10 percent owner
AP PHARMA INC /DE/
Current Name:HERON THERAPEUTICS, INC. /DE/		 0000818033 2009-10-19 10 percent owner
TRIMERIS INC
Current Name:SYNAGEVA BIOPHARMA CORP		 0000911326 2007-08-14 director
BIOCRYST PHARMACEUTICALS INC 0000882796 2007-08-06 10 percent owner
Synvista Therapeutics, Inc. 0000878903 2007-07-25 10 percent owner
ALLOS THERAPEUTICS INC 0001097264 2006-11-14 10 percent owner
GENOMIC HEALTH INC 0001131324 2006-04-25 director
TAPESTRY PHARMACEUTICALS, INC 0000891504 2006-04-05 10 percent owner
IDERA PHARMACEUTICALS, INC.
Current Name:Aceragen, Inc.		 0000861838 2006-03-24 10 percent owner
Ardea Biosciences, Inc./DE 0001103390 2005-07-14 10 percent owner
Innoviva, Inc. 0001080014 2005-06-30 director
NEUROGEN CORP 0000849043 2005-06-09 10 percent owner
VIROPHARMA INC 0000946840 2005-05-02 10 percent owner


Items 1 - 80

The information presented below contains only portions of the information presented in the referenced filing or filings.
You should consult the original filing for complete information. Hyperlinks to the forms are provided for your convenience.

Acquistion or Disposition Transaction Date Deemed Execution Date Issuer Form Transaction Type Direct or Indirect Ownership Number of Securities Transacted Number of Securities Owned Line Number Issuer CIK Security Name
D 2017-02-17   INCYTE CORP 4 D-Return --I 228326000.0000 0.0000 12 0000879169 0.375% Convertible Senior Note due 2018
A 2017-02-17   INCYTE CORP 4 A-Award --I 4487412.0000 24245586.0000 6 0000879169 Common Stock
A 2017-02-17   INCYTE CORP 4 A-Award --I 502779.0000 4353957.0000 5 0000879169 Common Stock
A 2017-02-17   INCYTE CORP 4 A-Award --I 4896067.0000 29141653.0000 7 0000879169 Common Stock
D 2017-02-17   INCYTE CORP 4 D-Return --I 25000000.0000 0.0000 11 0000879169 1.25% Convertible Senior Note due 2020
A 2017-02-17   INCYTE CORP 4 A-Award --I 121672.0000 767095.0000 9 0000879169 Common Stock
A 2017-02-17   INCYTE CORP 4 A-Award --I 111514.0000 645423.0000 8 0000879169 Common Stock
D 2017-02-17   INCYTE CORP 4 D-Return --I 5674000.0000 0.0000 14 0000879169 0.375% Convertible Senior Note due 2018
A 2017-02-17   INCYTE CORP 4 A-Award --I 491338.0000 3851178.0000 4 0000879169 Common Stock
D 2017-02-17   INCYTE CORP 4 D-Return --I 25000000.0000 0.0000 10 0000879169 0.375% Convertible Senior Note due 2018
D 2017-02-17   INCYTE CORP 4 D-Return --I 6050000.0000 0.0000 15 0000879169 1.25% Convertible Senior Note due 2020
D 2017-02-17   INCYTE CORP 4 D-Return --I 243450000.0000 0.0000 13 0000879169 1.25% Convertible Senior Note due 2020
A 2017-01-03   IDERA PHARMACEUTICALS, INC. 4 A-Award --I 14169.0000 1017950.0000 1 0000861838 Common Stock
A 2017-01-03   IDERA PHARMACEUTICALS, INC. 4 A-Award --I 14169.0000 125179.0000 3 0000861838 Common Stock
A 2017-01-03   IDERA PHARMACEUTICALS, INC. 4 A-Award --I 14169.0000 9323502.0000 2 0000861838 Common Stock
A 2016-12-30   INCYTE CORP 4 A-Award --I 189.0000 533909.0000 6 0000879169 Common Stock
A 2016-12-30   INCYTE CORP 4 A-Award --I 189.0000 19758174.0000 5 0000879169 Common Stock
A 2016-12-30   INCYTE CORP 4 A-Award --I 189.0000 3359840.0000 4 0000879169 Common Stock
A 2016-10-07   IDERA PHARMACEUTICALS, INC. 4 P-Purchase --I 2928596.0000 9309333.0000 3 0000861838 Common Stock
A 2016-10-07   IDERA PHARMACEUTICALS, INC. 4 P-Purchase --I 321404.0000 1003781.0000 2 0000861838 Common Stock
A 2016-10-03   IDERA PHARMACEUTICALS, INC. 4 A-Award --I 8299.0000 6380737.0000 2 0000861838 Common Stock
A 2016-10-03   IDERA PHARMACEUTICALS, INC. 4 A-Award --I 8299.0000 682377.0000 1 0000861838 Common Stock
A 2016-10-03   IDERA PHARMACEUTICALS, INC. 4 A-Award --I 8299.0000 111010.0000 3 0000861838 Common Stock
A 2016-09-30   INCYTE CORP 4 A-Award --I 201.0000 533720.0000 6 0000879169 Common Stock
A 2016-09-30   INCYTE CORP 4 A-Award --I 201.0000 3359651.0000 4 0000879169 Common Stock
A 2016-09-30   INCYTE CORP 4 A-Award --I 201.0000 19757985.0000 5 0000879169 Common Stock
A 2016-07-01   IDERA PHARMACEUTICALS, INC. 4 A-Award --I 13038.0000 6372438.0000 2 0000861838 Common Stock
A 2016-07-01   IDERA PHARMACEUTICALS, INC. 4 A-Award --I 13038.0000 102711.0000 3 0000861838 Common Stock
A 2016-07-01   IDERA PHARMACEUTICALS, INC. 4 A-Award --I 13038.0000 674078.0000 1 0000861838 Common Stock
A 2016-06-30   INCYTE CORP 4 A-Award --I 237.0000 533519.0000 6 0000879169 Common Stock
A 2016-06-30   INCYTE CORP 4 A-Award --I 237.0000 19757784.0000 5 0000879169 Common Stock
A 2016-06-30   INCYTE CORP 4 A-Award --I 237.0000 3359450.0000 4 0000879169 Common Stock
A 2016-06-13   IDERA PHARMACEUTICALS, INC. 4 A-Award --I 70000.0000 70000.0000 1 0000861838 Non-Qualified Stock Option (right to buy)
A 2016-05-27   INCYTE CORP 4 A-Award --I 15000.0000 15000.0000 1 0000879169 Non-Qualified Stock Options (right to buy)
A 2016-04-01   IDERA PHARMACEUTICALS, INC. 4 A-Award --I 10788.0000 6359400.0000 2 0000861838 Common Stock
A 2016-04-01   IDERA PHARMACEUTICALS, INC. 4 A-Award --I 10788.0000 661040.0000 1 0000861838 Common Stock
A 2016-04-01   IDERA PHARMACEUTICALS, INC. 4 A-Award --I 10788.0000 89673.0000 3 0000861838 Common Stock
A 2016-03-31   INCYTE CORP 4 A-Award --I 262.0000 533282.0000 6 0000879169 Common Stock
A 2016-03-31   INCYTE CORP 4 A-Award --I 262.0000 19757547.0000 5 0000879169 Common Stock
A 2016-03-31   INCYTE CORP 4 A-Award --I 262.0000 3359213.0000 4 0000879169 Common Stock
A 2016-03-17   INCYTE CORP 4 P-Purchase --I 24431.0000 19539142.0000 19 0000879169 Common Stock
D 2016-03-17   INCYTE CORP 4 M-Exempt --I 20000.0000 0.0000 24 0000879169 Non-Qualified Stock Options (right to buy)
A 2016-03-17   INCYTE CORP 4 M-Exempt --I 20000.0000 3319668.0000 11 0000879169 Common Stock
A 2016-03-17   INCYTE CORP 4 M-Exempt --I 20000.0000 533020.0000 13 0000879169 Common Stock
A 2016-03-17   INCYTE CORP 4 P-Purchase --I 13936.0000 3349130.0000 20 0000879169 Common Stock
A 2016-03-17   INCYTE CORP 4 P-Purchase --I 90179.0000 19757285.0000 23 0000879169 Common Stock
A 2016-03-17   INCYTE CORP 4 P-Purchase --I 2250.0000 3332534.0000 16 0000879169 Common Stock
A 2016-03-17   INCYTE CORP 4 P-Purchase --I 20659.0000 19514711.0000 17 0000879169 Common Stock
D 2016-03-17   INCYTE CORP 4 M-Exempt --I 20000.0000 0.0000 26 0000879169 Non-Qualified Stock Options (right to buy)
A 2016-03-17   INCYTE CORP 4 P-Purchase --I 9821.0000 3358951.0000 22 0000879169 Common Stock
A 2016-03-17   INCYTE CORP 4 P-Purchase --I 127964.0000 19667106.0000 21 0000879169 Common Stock
A 2016-03-17   INCYTE CORP 4 P-Purchase --I 97484.0000 19494052.0000 15 0000879169 Common Stock
A 2016-03-17   INCYTE CORP 4 P-Purchase --I 2660.0000 3335194.0000 18 0000879169 Common Stock
A 2016-03-17   INCYTE CORP 4 M-Exempt --I 20000.0000 19396568.0000 12 0000879169 Common Stock
A 2016-03-17   INCYTE CORP 4 P-Purchase --I 10616.0000 3330284.0000 14 0000879169 Common Stock
D 2016-03-17   INCYTE CORP 4 M-Exempt --I 20000.0000 0.0000 25 0000879169 Non-Qualified Stock Options (right to buy)
A 2016-03-15   INCYTE CORP 4 P-Purchase --I 179176.0000 19375386.0000 8 0000879169 Common Stock
A 2016-03-15   INCYTE CORP 4 P-Purchase --I 19513.0000 3299539.0000 7 0000879169 Common Stock
A 2016-03-15   INCYTE CORP 4 P-Purchase --I 19642.0000 3280026.0000 5 0000879169 Common Stock
A 2016-03-15   INCYTE CORP 4 P-Purchase --I 129.0000 3299668.0000 9 0000879169 Common Stock
A 2016-03-15   INCYTE CORP 4 P-Purchase --I 1182.0000 19376568.0000 10 0000879169 Common Stock
A 2016-03-15   INCYTE CORP 4 P-Purchase --I 180358.0000 19196210.0000 6 0000879169 Common Stock
A 2016-02-25   INCYTE CORP 4 P-Purchase --I 678.0000 3260384.0000 11 0000879169 Common Stock
A 2016-02-25   INCYTE CORP 4 P-Purchase --I 6022.0000 19015852.0000 12 0000879169 Common Stock
A 2016-02-24   INCYTE CORP 4 P-Purchase --I 20492.0000 19009830.0000 10 0000879169 Common Stock
A 2016-02-24   INCYTE CORP 4 P-Purchase --I 8111.0000 18966181.0000 6 0000879169 Common Stock
A 2016-02-24   INCYTE CORP 4 P-Purchase --I 2608.0000 3257398.0000 7 0000879169 Common Stock
A 2016-02-24   INCYTE CORP 4 P-Purchase --I 2308.0000 3259706.0000 9 0000879169 Common Stock
A 2016-02-24   INCYTE CORP 4 P-Purchase --I 23157.0000 18989338.0000 8 0000879169 Common Stock
A 2016-02-24   INCYTE CORP 4 P-Purchase --I 914.0000 3254790.0000 5 0000879169 Common Stock
A 2016-02-16   INCYTE CORP 4 P-Purchase --I 15187.0000 18958070.0000 18 0000879169 Common Stock
A 2016-02-16   INCYTE CORP 4 P-Purchase --I 1651.0000 3253876.0000 17 0000879169 Common Stock
A 2016-02-16   INCYTE CORP 4 P-Purchase --I 8250.0000 18942883.0000 16 0000879169 Common Stock
A 2016-02-16   INCYTE CORP 4 P-Purchase --I 67373.0000 18934633.0000 14 0000879169 Common Stock
A 2016-02-16   INCYTE CORP 4 P-Purchase --I 13490.0000 3244002.0000 11 0000879169 Common Stock
A 2016-02-16   INCYTE CORP 4 P-Purchase --I 7326.0000 3251328.0000 13 0000879169 Common Stock
A 2016-02-16   INCYTE CORP 4 P-Purchase --I 897.0000 3252225.0000 15 0000879169 Common Stock
A 2016-02-16   INCYTE CORP 4 P-Purchase --I 397079.0000 18743203.0000 10 0000879169 Common Stock
A 2016-02-16   INCYTE CORP 4 P-Purchase --I 43178.0000 3230512.0000 9 0000879169 Common Stock
A 2016-02-16   INCYTE CORP 4 P-Purchase --I 124057.0000 18867260.0000 12 0000879169 Common Stock

http://www.sec.gov/cgi-bin/own-disp

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Modified: 04/22/2016