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U.S. Securities and Exchange Commission


IONIS PHARMACEUTICALS INC (0000874015)
SIC: 2834 - Pharmaceutical Preparations
State location: CA | State of Inc.: CA | Fiscal Year End: 1231
formerly: ISIS PHARMACEUTICALS INC (until 2015-12-18)
Business Address
2855 GAZELLE COURT
CARLSBAD CA 92010
7609319200
 Mailing Address
2855 GAZELLE COURT
CARLSBAD CA 92010
Ownership Reports from: (Click on owner name to see other issuer holdings for the owner, or CIK for owner filings.)

Owner Filings Transaction Date Type of Owner
Devers Shannon L. 0002037721 2024-09-29 officer: EVP, Chief Human Resourses Ofc
Jenne Kyle 0001791857 2024-02-26 officer: EVP, Chf GL Pdt Str Ofcr
YANG MICHAEL J. 0001702283 2023-12-14 director
Birchler Brian 0001970151 2023-03-14 officer: EVP, Corp and Development Ops
Baroldi Joseph 0001813775 2022-01-31 officer: Chief Business Officer
Diaz Allene M. 0001773314 2021-06-03 director
Schneider Eugene 0001838539 2020-12-27 officer: EVP, Chf Clinical Develop Offc
Cadoret-Manier Onaiza 0001799355 2020-01-09 officer: Chief Corp Dev and Cml Officer
Swayze Eric 0001791058 2020-01-01 officer: SVP, Research
HERMAN JOAN E 0001248398 2019-06-10 director
Reikes Peter N 0001753652 2018-09-23 director
Hayden Michael R 0001352908 2018-09-20 director
McDevitt Damien 0001742277 2018-06-18 officer: Chief Business Officer
Boyce Sarah 0001629383 2015-01-01 officer: Chief Business Officer
LOSCALZO JOSEPH 0001276128 2014-02-03 director
Castleman Breaux 0001335073 2013-06-25 director
HOUGEN ELIZABETH L 0001074773 2013-01-01 officer: SVP, Finance and CFO
O'NEIL PATRICK R. 0001564926 2013-01-01 officer: SVP, Legal and General Counsel
Monia Brett P 0001537529 2012-01-01 director, officer: Senior Vice President
Geary Richard S 0001442730 2008-08-16 officer: Senior Vice President
XANTHOPOULOS KLEANTHIS G 0001283304 2007-12-03 officer: President of Regulus
JONAS JEFFREY M 0001042021 2007-02-01 officer: Executive Vice President
KLEIN JOSEPH III 0001206369 2005-12-13 director
LILLY ELI & CO 0000059478 2005-08-05 10 percent owner
Wedel Mark K 0001321261 2005-05-25 officer: VP & Chief Medical Officer
DiMarchi Richard D 0001311733 2004-12-14 director
Treble Michael J 0001311748 2004-12-14 officer: Vice President
DE HAAN HANS A 0001287259 2004-04-12 officer: VP, Drug Development
MCNEIL JOHN A 0001181558 2004-01-01 officer: VP, Infomatics
STEIN ARON 0001181562 2004-01-01 officer: VP-Regulatory Affairs&Quality
SKALETSKY MARK B 0001073379 2003-07-01 director
WENDER JOSEPH H 0001073384 2003-07-01 director
BERTHELSEN SPENCER R 0001181548 2003-07-01 director
MUTO FREDERICK T 0001181560 2003-07-01 director
REED JOHN C 0001181561 2003-07-01 director
GARIELI CHRISTOPHER 0001181553 2003-06-11 director
PARSHALL B LYNNE 0001073385 2003-05-09 director, officer: Executive Vice President, CFO
LOWENSTAM PATRICIA 0001073386 2003-05-09 officer: Vice President
BENNETT C FRANK 0001073387 2003-05-09 officer: Vice President
ECKER DAVID J 0001073388 2003-05-09 officer: Vice President
BROWN RICHARD K 0001181549 2003-05-09 officer: Vice President
COLE DOUGLAS L 0001181550 2003-05-09 officer: Vice President
LEVIN ARTHUR A 0001181556 2003-05-09 officer: Vice President
LUNDSTEDT KAREN S 0001181557 2003-05-09 officer: Vice President
HOLMLUD JON T 0001227367 2003-05-09 officer: Vice President
CROOKE STANLEY T 0000897667 2003-05-07 director, officer: Chairman, President, CEO


Items 1 - 80

The information presented below contains only portions of the information presented in the referenced filing or filings.
You should consult the original filing for complete information. Hyperlinks to the forms are provided for your convenience.

Acquistion or Disposition Transaction Date Deemed Execution Date Reporting Owner Form Transaction Type Direct or Indirect Ownership Number of Securities Transacted Number of Securities Owned Line Number Owner CIK Security Name
D 2025-03-11   Monia Brett P 4 S-Sale --D 140.0000 180980.0000 1 0001537529 Common Stock
A 2025-02-28   Swayze Eric 4 J-Other --D 415.0000 48432.0000 1 0001791058 Common Stock
A 2025-02-28   O'NEIL PATRICK R. 4 J-Other --D 554.0000 56799.0000 1 0001564926 Common Stock
A 2025-02-28   Monia Brett P 4 J-Other --D 437.0000 181120.0000 1 0001537529 Common Stock
A 2025-02-28   Geary Richard S 4 J-Other --D 415.0000 99492.0000 1 0001442730 Common Stock
A 2025-02-28   Birchler Brian 4 J-Other --D 414.0000 55465.0000 1 0001970151 Common Stock
A 2025-02-28   BENNETT C FRANK 4 J-Other --D 320.0000 93466.0000 1 0001073387 Common Stock
D 2025-02-20   O'NEIL PATRICK R. 4 S-Sale --D 1207.0000 56245.0000 1 0001564926 Common Stock
D 2025-02-04   O'NEIL PATRICK R. 4 S-Sale --D 6165.0000 57452.0000 1 0001564926 Common Stock
D 2025-02-04   Monia Brett P 4 S-Sale --D 38843.0000 180683.0000 1 0001537529 Common Stock
D 2025-01-31   Swayze Eric 4 S-Sale --D 1367.0000 48017.0000 2 0001791058 Common Stock
D 2025-01-31   Schneider Eugene 4 S-Sale --D 1484.0000 61056.0000 2 0001838539 Common Stock
D 2025-01-31   O'NEIL PATRICK R. 4 S-Sale --D 1406.0000 63617.0000 2 0001564926 Common Stock
D 2025-01-31   Monia Brett P 4 S-Sale --D 13242.0000 219526.0000 2 0001537529 Common Stock
D 2025-01-31   HOUGEN ELIZABETH L 4 S-Sale --D 1523.0000 110500.0000 2 0001074773 Common Stock
D 2025-01-31   Geary Richard S 4 S-Sale --D 1406.0000 99077.0000 2 0001442730 Common Stock
D 2025-01-31   BENNETT C FRANK 4 S-Sale --D 1327.0000 93146.0000 2 0001073387 Common Stock
A 2025-01-30   Swayze Eric 4 A-Award --D 3714.0000 49384.0000 1 0001791058 Common Stock
A 2025-01-30   Schneider Eugene 4 A-Award --D 4032.0000 62540.0000 1 0001838539 Common Stock
A 2025-01-30   O'NEIL PATRICK R. 4 A-Award --D 3820.0000 65023.0000 1 0001564926 Common Stock
A 2025-01-30   Monia Brett P 4 A-Award --D 25372.0000 232768.0000 1 0001537529 Common Stock
A 2025-01-30   HOUGEN ELIZABETH L 4 A-Award --D 4138.0000 112023.0000 1 0001074773 Common Stock
A 2025-01-30   Geary Richard S 4 A-Award --D 3820.0000 100483.0000 1 0001442730 Common Stock
A 2025-01-30   BENNETT C FRANK 4 A-Award --D 3607.0000 94473.0000 1 0001073387 Common Stock
D 2025-01-16   Swayze Eric 4 S-Sale --I 22.0000 184.0000 4 0001791058 Common Stock
D 2025-01-16   Swayze Eric 4 S-Sale --D 7154.0000 45670.0000 2 0001791058 Common Stock
D 2025-01-16   Schneider Eugene 4 S-Sale --D 6523.0000 58508.0000 2 0001838539 Common Stock
D 2025-01-16   O'NEIL PATRICK R. 4 S-Sale --D 7360.0000 61203.0000 2 0001564926 Common Stock
D 2025-01-16   Monia Brett P 4 S-Sale --D 33445.0000 207396.0000 2 0001537529 Common Stock
D 2025-01-16   HOUGEN ELIZABETH L 4 S-Sale --D 8870.0000 107885.0000 2 0001074773 Common Stock
D 2025-01-16   Geary Richard S 4 S-Sale --D 7072.0000 96663.0000 2 0001442730 Common Stock
D 2025-01-16   Devers Shannon L. 4 S-Sale --D 4267.0000 15937.0000 2 0002037721 Common Stock
D 2025-01-16   Birchler Brian 4 S-Sale --D 5400.0000 55051.0000 2 0001970151 Common Stock
D 2025-01-16   BENNETT C FRANK 4 S-Sale --D 6752.0000 90866.0000 2 0001073387 Common Stock
D 2025-01-16   Baroldi Joseph 4 S-Sale --I 1029.0000 3071.0000 4 0001813775 Common Stock
D 2025-01-16   Baroldi Joseph 4 S-Sale --D 3401.0000 25017.0000 2 0001813775 Common Stock
D 2025-01-15   YANG MICHAEL J. 4 M-Exempt --D 1931.0000 7939.0000 2 0001702283 Restricted Stock Unit
A 2025-01-15   YANG MICHAEL J. 4 M-Exempt --D 1931.0000 1931.0000 1 0001702283 Common Stock
D 2025-01-15   Swayze Eric 4 M-Exempt --I 49.0000 622.0000 9 0001791058 Restricted Stock Unit
A 2025-01-15   Swayze Eric 4 A-Award --I 245.0000 671.0000 8 0001791058 Restricted Stock Unit
D 2025-01-15   Swayze Eric 4 M-Exempt --D 19111.0000 60617.0000 7 0001791058 Restricted Stock Unit
A 2025-01-15   Swayze Eric 4 A-Award --D 33000.0000 79728.0000 6 0001791058 Restricted Stock Unit
A 2025-01-15   Swayze Eric 4 A-Award --D 22000.0000 64482.0000 5 0001791058 Performance Restricted Stock Units
A 2025-01-15   Swayze Eric 4 M-Exempt --I 49.0000 206.0000 3 0001791058 Common Stock
A 2025-01-15   Swayze Eric 4 M-Exempt --D 19111.0000 52824.0000 1 0001791058 Common Stock
D 2025-01-15   Schneider Eugene 4 M-Exempt --D 17372.0000 60936.0000 5 0001838539 Restricted Stock Unit
A 2025-01-15   Schneider Eugene 4 A-Award --D 33000.0000 78308.0000 4 0001838539 Restricted Stock Unit
A 2025-01-15   Schneider Eugene 4 A-Award --D 22000.0000 65437.0000 3 0001838539 Performance Restricted Stock Units
A 2025-01-15   Schneider Eugene 4 M-Exempt --D 17372.0000 65031.0000 1 0001838539 Common Stock
D 2025-01-15   O'NEIL PATRICK R. 4 M-Exempt --D 19690.0000 60724.0000 5 0001564926 Restricted Stock Unit
A 2025-01-15   O'NEIL PATRICK R. 4 A-Award --D 33000.0000 80414.0000 4 0001564926 Restricted Stock Unit
A 2025-01-15   O'NEIL PATRICK R. 4 A-Award --D 22000.0000 64801.0000 3 0001564926 Performance Restricted Stock Units
A 2025-01-15   O'NEIL PATRICK R. 4 M-Exempt --D 19690.0000 68563.0000 1 0001564926 Common Stock
D 2025-01-15   Monia Brett P 4 M-Exempt --D 73448.0000 252159.0000 5 0001537529 Restricted Stock Unit
A 2025-01-15   Monia Brett P 4 A-Award --D 129395.0000 325607.0000 4 0001537529 Restricted Stock Unit
A 2025-01-15   Monia Brett P 4 A-Award --D 169950.0000 630201.0000 3 0001537529 Performance Restricted Stock Units
A 2025-01-15   Monia Brett P 4 M-Exempt --D 73448.0000 240841.0000 1 0001537529 Common Stock
A 2025-01-15   Jenne Kyle 4 A-Award --D 28050.0000 28050.0000 2 0001791857 Restricted Stock Unit
A 2025-01-15   Jenne Kyle 4 A-Award --D 18700.0000 18700.0000 1 0001791857 Performance Restricted Stock Units
D 2025-01-15   HOUGEN ELIZABETH L 4 M-Exempt --D 23887.0000 84669.0000 5 0001074773 Restricted Stock Unit
A 2025-01-15   HOUGEN ELIZABETH L 4 A-Award --D 46500.0000 108556.0000 4 0001074773 Restricted Stock Unit
A 2025-01-15   HOUGEN ELIZABETH L 4 A-Award --D 31000.0000 86635.0000 3 0001074773 Performance Restricted Stock Units
A 2025-01-15   HOUGEN ELIZABETH L 4 M-Exempt --D 23887.0000 116755.0000 1 0001074773 Common Stock
D 2025-01-15   Geary Richard S 4 M-Exempt --D 18901.0000 60724.0000 5 0001442730 Restricted Stock Unit
A 2025-01-15   Geary Richard S 4 A-Award --D 33000.0000 79625.0000 4 0001442730 Restricted Stock Unit
A 2025-01-15   Geary Richard S 4 A-Award --D 22000.0000 64801.0000 3 0001442730 Performance Restricted Stock Units
A 2025-01-15   Geary Richard S 4 M-Exempt --D 18901.0000 103735.0000 1 0001442730 Common Stock
D 2025-01-15   Devers Shannon L. 4 M-Exempt --D 12295.0000 63226.0000 5 0002037721 Restricted Stock Unit
A 2025-01-15   Devers Shannon L. 4 A-Award --D 33000.0000 75521.0000 4 0002037721 Restricted Stock Unit
A 2025-01-15   Devers Shannon L. 4 A-Award --D 22000.0000 22000.0000 3 0002037721 Performance Restricted Stock Units
A 2025-01-15   Devers Shannon L. 4 M-Exempt --D 12295.0000 20204.0000 1 0002037721 Common Stock
D 2025-01-15   Birchler Brian 4 M-Exempt --D 14283.0000 63090.0000 5 0001970151 Restricted Stock Unit
A 2025-01-15   Birchler Brian 4 A-Award --D 33000.0000 77373.0000 4 0001970151 Restricted Stock Unit
A 2025-01-15   Birchler Brian 4 A-Award --D 22000.0000 53338.0000 3 0001970151 Performance Restricted Stock Units
A 2025-01-15   Birchler Brian 4 M-Exempt --D 14283.0000 60451.0000 1 0001970151 Common Stock
D 2025-01-15   BENNETT C FRANK 4 M-Exempt --D 18011.0000 38489.0000 5 0001073387 Restricted Stock Unit
A 2025-01-15   BENNETT C FRANK 4 A-Award --D 33000.0000 56500.0000 4 0001073387 Restricted Stock Unit
A 2025-01-15   BENNETT C FRANK 4 A-Award --D 22000.0000 63482.0000 3 0001073387 Performance Restricted Stock Units
A 2025-01-15   BENNETT C FRANK 4 M-Exempt --D 18011.0000 97618.0000 1 0001073387 Common Stock
D 2025-01-15   Baroldi Joseph 4 M-Exempt --I 2460.0000 8324.0000 9 0001813775 Restricted Stock Unit

http://www.sec.gov/cgi-bin/own-disp

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Modified: 04/22/2016