Business Segment and Geographical Information - Schedule of Business Segment Information (Details) - USD ($) $ in Millions	3 Months Ended		9 Months Ended
	Sep. 30, 2023	Oct. 01, 2022	Sep. 30, 2023	Oct. 01, 2022
Segment Reporting Information [Line Items]
Revenues	$ 10,574	$ 10,677	$ 31,971	$ 33,465
Segment Income	1,864	1,710	5,005	6,532
Restructuring and other costs	(84)	(33)	(379)	(59)
Amortization of acquisition-related intangible assets			(1,775)	(1,803)
Interest income	246	68	570	122
Interest expense	(359)	(173)	(985)	(457)
Other income/(expense)	14	(4)	(32)	(139)
Income before income taxes	1,765	1,601	4,558	6,058
Total Reportable Segments
Segment Reporting Information [Line Items]
Segment Income	2,560	2,370	7,260	8,425
Total Reportable Segments | Life Sciences Solutions
Segment Reporting Information [Line Items]
Revenues	2,433	2,962	7,508	10,485
Segment Income	872	1,039	2,525	4,542
Restructuring and other costs	(20)		(100)
Total Reportable Segments | Analytical Instruments
Segment Reporting Information [Line Items]
Revenues	1,754	1,621	5,226	4,746
Segment Income	468	386	1,321	1,031
Restructuring and other costs	(8)		(31)
Total Reportable Segments | Specialty Diagnostics
Segment Reporting Information [Line Items]
Revenues	1,083	1,065	3,300	3,648
Segment Income	283	220	860	816
Restructuring and other costs	1		(9)
Total Reportable Segments | Laboratory Products and Biopharma Services
Segment Reporting Information [Line Items]
Revenues	5,728	5,585	17,322	16,564
Segment Income	937	725	2,554	2,036
Restructuring and other costs	(52)		(228)
Eliminations
Segment Reporting Information [Line Items]
Revenues	(424)	(556)	(1,385)	(1,978)
Segment Reconciling Items
Segment Reporting Information [Line Items]
Cost of revenues adjustments	(14)	(22)	(73)	(41)
Selling, general and administrative expenses adjustments	(14)	(11)	(28)	10
Restructuring and other costs	(84)	(33)	(379)	(59)
Amortization of acquisition-related intangible assets	$ (584)	$ (594)	$ (1,775)	$ (1,803)