Business Segment and Geographical Information - Schedule of Business Segment Information (Details) - USD ($) $ in Millions	3 Months Ended
	Apr. 01, 2023	Apr. 02, 2022
Segment Reporting Information [Line Items]
Revenues	$ 10,710	$ 11,818
Segment Income	1,563	2,821
Restructuring and other costs	(112)	(2)
Amortization of acquisition-related intangible assets	(606)	(609)
Interest income	146	18
Interest expense	(300)	(136)
Other income/(expense)	(46)	(163)
Income before income taxes	1,363	2,540
Total Reportable Segments
Segment Reporting Information [Line Items]
Segment Income	2,330	3,450
Total Reportable Segments | Life Sciences Solutions
Segment Reporting Information [Line Items]
Revenues	2,612	4,231
Segment Income	836	2,176
Restructuring and other costs	(60)
Total Reportable Segments | Analytical Instruments
Segment Reporting Information [Line Items]
Revenues	1,723	1,518
Segment Income	421	301
Restructuring and other costs	0
Total Reportable Segments | Specialty Diagnostics
Segment Reporting Information [Line Items]
Revenues	1,108	1,482
Segment Income	280	353
Restructuring and other costs	(8)
Total Reportable Segments | Laboratory Products and Biopharma Services
Segment Reporting Information [Line Items]
Revenues	5,763	5,442
Segment Income	793	620
Restructuring and other costs	(43)
Eliminations
Segment Reporting Information [Line Items]
Revenues	(496)	(855)
Segment Reconciling Items
Segment Reporting Information [Line Items]
Cost of revenues adjustments	(41)	(11)
Selling, general and administrative expenses adjustments	(8)	(7)
Restructuring and other costs	(112)	(2)
Amortization of acquisition-related intangible assets	$ (606)	$ (609)