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Nature of Operations and Summary of Significant Accounting Policies - Additional Accounting Policy and Balance Sheet Disclosures (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Noncontrolling Interest [Line Items]      
Equity method investments $ 369 $ 576  
Fair value of investments 7 217  
Cost method investments 55 22  
Investments measured at NAV 22 16  
Currency transaction gains $ 62 $ 25 $ 24
PPD-SNBL K.K.      
Noncontrolling Interest [Line Items]      
Ownership percentage, parent 60.00%    
Ownership interest, noncontrolling owners 40.00%