Shareholders' Equity (Tables)

3 Months Ended

Mar. 31, 2018

Class of Stock [Line Items]

Schedule of unrealized gain or loss on derivatives of warrant liability

February 21, 2018 Pre Down Round (Equity)	1,233,086
Change in Fair Value (deemed dividend)	9,649
February 21, 2018 Post Down Round (Liability)	1,242,735
Change in Fair Value	(541,145	)
March 31, 2018, ending balance	701,590

Schedule of key assumptions used model at inception

	February 21, 2018 Pre Round Down			February 21, 2018 Post Down Round			March 31, 2018
Stock Price	$	0.96		$	0.96		$	0.57
Exercise Price	$	1.31		$	0.94		$	0.94
Term (years)		4.75			4.75			4.65
Risk Free Rate		2.69	%		2.69	%		2.57	%
Volatility		152.9	%		152.9	%		140.4	%

Schedule of outstanding stock warrants

	Number of Shares			Average Exercise Price		Expiration Date
Outstanding - December 31, 2017		1,644,359		$	.78
Granted		689,893			2.82	February, 2023
Exercised		(313	)		15.20
Outstanding, March 31, 2018		2,333,939		$	10.84
Warrants exercisable at March 31, 2018		2,333,939

Schedule of the company's stock options

	Number of Shares Underlying Options		Weighted Average Exercise Price		Weighted Average Grant Date Fair Value		Weighted Average Remaining Contractual Life		Aggregate Intrinsic Value (1)
Outstanding at December 31, 2017		1,434	$	154.78	$	4.78		3.61		-
For the three months ended March 31, 2018
Granted		-		-		-		-
Exercised		-		-		-		-
Expired		-		-		-		-
Outstanding at March 31, 2018		1,434	$	154.78	$	4.78		3.61		-
Outstanding and Exercisable at March 31, 2018		213	$	154.78	$	4.78		3.61		-

(1) The aggregate intrinsic value is based on the $0.57 closing price as of March 29, 2018 for the Company's Common Stock.

Schedule of following information applies to options outstanding

Options Outstanding						Options Exercisable
Exercise Price		Number of Shares Underlying Options		Weighted Average Remaining Contractual Life		Number Exercisable		Exercise Price
$	96.00		28		3.38		28	$	96.00
$	160.00		1,406		3.38		663	$	160.00
			1,434		3.38		691

Series D warrant liability [Member]

Class of Stock [Line Items]

Schedule of unrealized gain or loss on derivatives of warrant liability

March 13, 2018 Pre Modification - Equity	1,096,758
Change in Fair Value due to modification	89,827
March 13, 2018 Reclass Liability	1,186,585
Change in Fair Value	(138,207	)
March 31, 2018 Fair Value	1,048,378

Schedule of key assumptions used model at inception

	March 13, 2018			March 31, 2018
Stock Price	$	0.64		$	0.57
Exercise Price	$	0.94		$	0.94
Term (years)		4.50			4.45
Risk Free Rate		2.62	%		2.57	%
Volatility		140.4	%		140.4	%

Series A warrant liability [Member]

Class of Stock [Line Items]

Schedule of unrealized gain or loss on derivatives of warrant liability

	February 21, 2018			March 31, 2018
Stock Price	$	0.9600		$	0.57
Exercise Price	$	0.95		$	0.95
Term (years)		5.00			4.90
Risk Free Rate		2.69	%		2.56	%
Volatility		152.9	%		140.4	%

Schedule of outstanding stock warrants

February 21, 2018	$	6,216,073
Change in Fair Value		(1,716,830	)
March 31, 2018	$	4,499,243

Series E warrant liability [Member]

Class of Stock [Line Items]

Schedule of unrealized gain or loss on derivatives of warrant liability

March 13, 2018 Pre Modification - Equity	2,390,687
Change in Fair Value due to modification	145,085
March 13, 2018 Reclass Liability	2,535,772
Change in Fair Value	(295,226	)
March 31, 2018 Fair Value	2,240,546

Schedule of key assumptions used model at inception

	March 13, 2018			March 31, 2018
Stock Price	$	0.64		$	0.57
Exercise Price	$	0.94		$	0.94
Term (years)		4.58			4.53
Risk Free Rate		2.62	%		2.57	%
Volatility		140.4	%		140.4	%