-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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 dvJqeJPd10LOc/3XJhhWcg==

<SEC-DOCUMENT>0001294092-04-000001.txt : 20040617
<SEC-HEADER>0001294092-04-000001.hdr.sgml : 20040617
<ACCEPTANCE-DATETIME>20040617145028
ACCESSION NUMBER:		0001294092-04-000001
CONFORMED SUBMISSION TYPE:	3
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20040616
FILED AS OF DATE:		20040617

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Mullen Michael James
		CENTRAL INDEX KEY:			0001294092

	FILING VALUES:
		FORM TYPE:		3
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-06533
		FILM NUMBER:		04868612

	BUSINESS ADDRESS:	
		BUSINESS PHONE:		508-380-9520

	MAIL ADDRESS:	
		STREET 1:		11 ARBOR CIRCLE
		CITY:			NATICK
		STATE:			MA
		ZIP:			01760

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			BOSTON LIFE SCIENCES INC /DE
		CENTRAL INDEX KEY:			0000094784
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				870277826
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		137 NEWBURY STREET
		STREET 2:		8TH FLOOR
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02116
		BUSINESS PHONE:		6174250200

	MAIL ADDRESS:	
		STREET 1:		137 NEWBURY STREET
		STREET 2:		8TH FLOOR
		CITY:			BOSTON
		STATE:			MA
		ZIP:			02116

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	GREENWICH PHARMACEUTICALS INC
		DATE OF NAME CHANGE:	19920703

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	STRATEGIC MEDICAL RESEARCH CORP /DE
		DATE OF NAME CHANGE:	19790521
</SEC-HEADER>
<DOCUMENT>
<TYPE>3
<SEQUENCE>1
<FILENAME>primary_doc.xml
<DESCRIPTION>PRIMARY DOCUMENT
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2004-06-16</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0000094784</issuerCik>
        <issuerName>BOSTON LIFE SCIENCES INC /DE</issuerName>
        <issuerTradingSymbol>BLSI</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001294092</rptOwnerCik>
            <rptOwnerName>Mullen Michael James</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>11 ARBOR CIRCLE</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>NATICK</rptOwnerCity>
            <rptOwnerState>MA</rptOwnerState>
            <rptOwnerZipCode>01760</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>1000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>Trustee under the MICHAEL J. MULLEN LIVING TRUST, dated April 22, 2002, and any amendments thereto.</value>
                    <footnoteId id="F1"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">The MICHAEL J. MULLEN LIVING TRUST is a revocable trust.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>Michael James Mullen</signatureName>
        <signatureDate>2004-06-17</signatureDate>
    </ownerSignature>
</ownershipDocument>

</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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