-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
 MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen
 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 WLF5RSBj0GPaO/ybamDr+Va2OT0Lxhls0dz5DfZblmTcZw2yNHEw0CmEyCmOqOla
 H+N1Re02ZRYfaulq9jOEeQ==

<SEC-DOCUMENT>0001209191-08-000674.txt : 20080103
<SEC-HEADER>0001209191-08-000674.hdr.sgml : 20080103
<ACCEPTANCE-DATETIME>20080103115355
ACCESSION NUMBER:		0001209191-08-000674
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20080102
FILED AS OF DATE:		20080103
DATE AS OF CHANGE:		20080103

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			ALSERES PHARMACEUTICALS INC /DE
		CENTRAL INDEX KEY:			0000094784
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				870277826
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		85 MAIN STREET
		CITY:			HOPKINTON
		STATE:			MA
		ZIP:			01748
		BUSINESS PHONE:		508-497-2360

	MAIL ADDRESS:	
		STREET 1:		85 MAIN STREET
		CITY:			HOPKINTON
		STATE:			MA
		ZIP:			01748

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	BOSTON LIFE SCIENCES INC /DE
		DATE OF NAME CHANGE:	19950706

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	GREENWICH PHARMACEUTICALS INC
		DATE OF NAME CHANGE:	19920703

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	STRATEGIC MEDICAL RESEARCH CORP /DE
		DATE OF NAME CHANGE:	19790521

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			RICE KENNETH L JR
		CENTRAL INDEX KEY:			0001126350
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-06533
		FILM NUMBER:		08504712

	BUSINESS ADDRESS:	
		STREET 1:		650 TOWN CENTER DRIVE 20TH FLOOR
		CITY:			COSTA MESA
		STATE:			CA
		ZIP:			92626-1925
		BUSINESS PHONE:		7145401235

	MAIL ADDRESS:	
		STREET 1:		C/O 85 MAIN STREET
		CITY:			HOPKINTON
		STATE:			MA
		ZIP:			01748
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>b67980kr.xml
<DESCRIPTION>MAIN DOCUMENT DESCRIPTION
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2008-01-02</periodOfReport>

    <issuer>
        <issuerCik>0000094784</issuerCik>
        <issuerName>ALSERES PHARMACEUTICALS INC /DE</issuerName>
        <issuerTradingSymbol>ALSE</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001126350</rptOwnerCik>
            <rptOwnerName>RICE KENNETH L JR</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O ALSERES PHARMACEUTICALS, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>85 MAIN STREET</rptOwnerStreet2>
            <rptOwnerCity>HOPKINTON</rptOwnerCity>
            <rptOwnerState>MA</rptOwnerState>
            <rptOwnerZipCode>01748</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>EXEC VP OF FIN &amp; ADMIN &amp; CFO</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2008-01-02</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>4485</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>4485</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <derivativeTable></derivativeTable>

    <ownerSignature>
        <signatureName>/s/ Kenneth L. Rice, Jr.</signatureName>
        <signatureDate>2008-01-03</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----