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Consolidated Statements of Cash Flows (USD $)
12 Months Ended 254 Months Ended
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2013
Cash flows from operating activities:      
Net loss $ (941,529) $ (1,645,476) $ (199,635,073)
Adjustments to reconcile net loss to net cash used for operating activities:      
Purchased in-process research and development     12,146,544
Write-off of acquired technology     3,500,000
Loss on disposition of assets     3,391
Interest expense settled through issuance of notes payable     350,500
Expenses satisfied with the issuance of stock     28,680
Forgiveness of debt     (476,837)
Gain on early extinguishment of debt     (6,277,100)
Non-cash gain on restricted stock valuation     (58,814)
Non-cash interest expense 448,104   4,414,498
Non-cash charges related to options, warrants and common stock     11,115,437
Amortization of financing costs     25,188
Amortization and depreciation 1,186 1,289 2,893,141
Receipt of marketable securities (190,000)   (190,000)
Loss on sale of marketable securities 263,154   263,154
Gain on sale of contingent liability 25,000   25,000
Changes in operating assets and liabilities:      
(Increase) decrease in prepaid expenses and other current assets (966) 2,245 503,642
(Increase) decrease in deferred charges 3,687 (64,514) (60,827)
(Decrease) increase in accounts payable and accrued expenses (1,222,660) 68,169 759,911
Increase (decrease) in accrued interest payable 5,630 432,835 8,253,262
Increase (decrease) in deferred revenue (73,730) 201,577 127,847
Increase (decrease) in current liabilities (14,805) 17,676 2,871
Increase (decrease) in other long-term liabilities 10,000 33,750 43,750
Net cash used for operating activities (1,686,929) (952,449) (162,241,835)
Cash flows from investing activities:      
Cash acquired through Merger     1,758,037
Purchases of property and equipment     (1,654,487)
Proceeds from the sale of property and equipment     3,430
Purchases of marketable securities     (132,004,923)
Sales and maturities of marketable securities 884,359   132,889,282
Net cash provided by investing activities 884,359   991,339
Cash flows from financing activities:      
Proceeds from issuance of common stock     66,731,339
Buyback of common stock   (1,866) (28,222)
Advances from related party 175,000 325,000 500,000
Net proceeds from issuance of preferred stock     39,922,170
Preferred stock conversion inducement     (600,564)
Net proceeds from issuance of promissory notes 725,000 510,000 59,720,000
Proceeds from issuance of convertible debentures     9,000,000
Principal payments of notes payable/repurchase of debt     (7,750,667)
Dividend payments on Series E Cumulative Convertible Preferred Stock     (516,747)
Payments of financing costs     (5,612,855)
Net cash provided by financing activities 900,000 833,134 161,364,454
Net (decrease) increase in cash and cash equivalents 97,430 (119,315) 113,958
Cash and cash equivalents, beginning of period 16,528 135,843  
Cash and cash equivalents, end of period 113,958 16,528 113,958
Supplemental cash flow disclosures:      
Cash paid for interest     628,406
Supplemental disclosure of non-cash investing and financing activity:      
Conversion of notes payable to common stock   5,827,588 13,000,000
Capital contribution related to forgiveness of accrued interest     6,328,306
Accrued interest reclassified in connection with conversion of Series F convertible redeemable preferred stock to common stock     640,874
Receipt of marketable securities as payment for license agreement   1,146,000 1,146,000
Conversion of notes payable to future royalties   16,000,000 16,000,000
Net change in unrealized holding gains and losses 315,854   315,854
Accretion of Series F preferred stock (20,942) (21,057) (20,942)
Net gain on debt modification 682,670   682,670
Gain on release of contingent liability $ 16,000,000   $ 16,000,000