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Consolidated Statements of Comprehensive Loss (USD $)
12 Months Ended 242 Months Ended
Dec. 31, 2012
Dec. 31, 2011
Dec. 31, 2012
Consolidated Statements of Comprehensive Loss [Abstract]      
Revenues $ 530,720   $ 1,430,720
Operating expenses:      
General and administrative 1,665,605 2,032,946 70,413,744
Research and development 50,750 93,319 116,092,348
Sublicense and option fees 26,536   26,536
Purchased in-process research and development      12,146,544
Operating expenses before accrual reversal 1,742,891 2,126,265 198,745,921
Accrual reversal   (561,195) (561,195)
Total operating expenses 1,742,891 1,565,070 198,184,726
Loss from operations (1,212,171) (1,565,070) (196,754,006)
Interest expense (434,551) (1,838,484) (14,923,661)
Investment income 341 689 7,705,345
Other income (expense), net 905 43,814 (1,473,159)
Gain on early extinguishment of debt     6,277,100
Forgiveness of debt    476,837 476,837
Net loss (1,645,476) (2,882,214) (198,691,544)
Preferred stock beneficial conversion feature     (8,062,712)
Accrual of preferred stock dividends and modification of warrants held by preferred stock stockholders     (1,229,589)
Net loss attributable to common stockholders (1,645,476) (2,882,214) (207,983,845)
Other comprehensive income Net change in unrealized loss on marketable securities (277,837) (31,367) 309,204
Comprehensive loss $ (1,923,313) $ (2,913,581) $ 208,293,049
Basic and diluted net loss attributable to common stockholders per share $ (0.06) $ (0.10)  
Weighted average common shares outstanding 30,635,720 29,626,072