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Consolidated Statements of Cash Flows (USD $)
12 Months Ended 230 Months Ended
Dec. 31, 2011
Dec. 31, 2010
Dec. 31, 2011
Cash flows from operating activities:      
Net income (loss) $ (2,882,214) $ 512,419 $ (197,046,068)
Adjustments to reconcile net loss to net cash used for operating activities:      
Purchased in-process research and development     12,146,544
Write-off of acquired technology     3,500,000
Loss on disposition of assets 3,391   3,391
Interest expense settled through issuance of notes payable     350,500
Expenses satisfied with the issuance of stock 28,680   28,680
Forgiveness of debt (476,837)   (476,837)
Gain on early extinguishment of debt   (6,277,100) (6,277,100)
Non-cash gain on restricted stock valuation (58,814)   (58,814)
Non-cash interest expense   741,471 3,966,394
Non-cash charges for options, warrants and common stock 834 61,722 11,115,437
Amortization of financing costs 6,949 18,239 25,188
Amortization and depreciation 40,751 58,598 2,890,666
Changes in current assets and liabilities:      
Decrease in prepaid expenses and other current assets 9,108 3,055 700,498
(Decrease) increase in accounts payable and accrued expenses (889,742) 116,966 1,914,402
Increase in accrued interest payable 1,829,516 1,865,457 7,814,797
Decrease in accrued lease (96,425) (51,494)  
Net cash used for operating activities (2,484,803) (2,950,667) (159,402,322)
Cash flows from investing activities:      
Cash acquired through merger     1,758,037
Purchases of property and equipment (2,373)   (1,654,487)
Proceeds from the sale of property and equipment 3,430   3,430
Decrease (increase) in security deposits and other assets 184,763 34,865 (200,135)
Decrease in indemnity fund 115,568 152  
Purchases of marketable securities     (132,004,923)
Sales and maturities of marketable securities     132,004,923
Net cash provided by (used for) investing activities 301,388 35,017 (93,155)
Cash flows from financing activities:      
Proceeds from issuance of common stock     66,731,339
Funds used to buyback common stock (18,256) (8,100) (26,356)
Proceeds from issuance of preferred stock     39,922,170
Preferred stock conversion inducement     (600,564)
Proceeds from issuance of promissory notes 2,240,000 3,310,000 58,485,000
Proceeds from issuance of convertible debentures     9,000,000
Principal payments of notes payable/repurchase of debt (1,000) (602,700) (7,750,667)
Dividend payments Series E Cumulative Convertible Preferred Stock     (516,747)
Payments related to financing costs     (5,612,855)
Net cash provided by financing activities 2,220,744 2,699,200 159,631,320
Net increase (decrease) in cash and cash equivalents 37,329 (216,450) 135,843
Cash and cash equivalents, beginning of period 98,514 314,964  
Cash and cash equivalents, end of period 135,843 98,514 135,843
Supplemental cash flow disclosures:      
Cash paid for interest     628,406
Supplemental disclosure of non-cash financing activity:      
Conversion of notes payable to common stock 7,172,412   7,172,412
Capital contribution related to forgiveness of accrued interest 6,328,306   6,328,306
Accrued interest reclassified in connection with conversion of Series F convertible redeemable preferred stock to common stock $ 640,874   $ 640,874