Stockholders' Equity (Tables)

12 Months Ended

Dec. 31, 2015

Schedule of options and equity estimated based on weighted average assumptions

were estimated based on the following weighted average assumptions:

	Year Ended December 31,
	2015	2014	2013
Risk-free interest rate	1.32%-1.72%	1.66%-1.72%	0.14%-1.40%
Expected dividend yield	0	0	0
Expected life	2.5-5 years	5 years	1-5 years
Expected volatility	83.840%-85.220%	84.497%-92.631%	89.727%-118.22%
Weighted average grant date fair value for options and equity warrants issued	$0.15 per option/warrant for 825,000 options/equity warrants	$0.18 per option for 1,314,284 options	$0.14 per option/warrant for 4,120,000 options/equity warrants

Schedule of warrants outstanding and exercisable

Information regarding warrants outstanding and exercisable into shares of common stock is summarized below:

	2013						2014							2015
	Shares		Warrant Price		Weighted Average Exercise Price		Shares			Warrant Price		Weighted Average Exercise Price		Shares			Warrant Price		Weighted Average Exercise Price
Outstanding, beginning of year		11,128,246		0.51-2.00	$	1.44		13,228,246			0.25-2.00	$	1.26		2,399,058			0.25-2.00	$	0.56
Granted		2,100,000		0.25-0.50	$	0.33		—			—	$	—		25,000			0.09	$	0.09
Forfeited		—		—		—		(10,829,188	)		0.29-1.65		1.41		(657,862	)		0.51-1.55		0.77
Exercised		—		—		—		—			—		—		—			—		—
Outstanding, end of year		13,228,246		0.25 –2.00	$	1.26		2,399,058			0.25-2.00	$	0.56		1,766,196			0.09-2.00	$	0.48
Exercisable		11,328,246		0.50-2.00	$	1.42		2,399,058			0.25-2.00	$	0.56		1,766,196			0.09-2.00		$ 0. 48
Weighted average remaining contractual life		1.5 years						4.8 years							4.4 years
Years exercisable		2014-2023						2014-2023							2017-2023

1990 Equity Incentive Plans [Member]

Schedule of stock option activity

Information regarding the options approved by the Board of Directors under the 1990 Stock Option Plan is summarized below:

	2013							2014						2015
	Shares			Option Price		Weighted Average Exercise Price		Shares		Option Price		Weighted Average Exercise Price		Shares		Option Price		Weighted Average Exercise Price
Outstanding, beginning of year		200,000			2.75	$	2.75		—		—	$	—		—		—	$	—
Granted		—			—		—		—		—		—		—		—		—
Forfeited		(200,000	)		2.75		2.75		—		—		—		—		—		—
Exercised		—			—		—		—		—		—		—		—		—
Outstanding, end of year		—		$	—	$	—		—	$	—	$	—		—	$	—	$	—
Exercisable, end of year		—		$	—	$	—		—	$	—	$	—		—	$	—	$	—
Weighted average remaining contractual life (years)		0 years							0 years						0 years
Available for future grants		—							—						—

2004 Equity Incentive Plans [Member]

Schedule of stock option activity

Information regarding the options approved by the Board of Directors under Equity Plan of 2004 is summarized below:

	2013							2014							2015
	Shares			Option Price		Weighted Average Exercise Price		Shares			Option Price		Weighted Average Exercise Price		Shares			Option Price		Weighted Average Exercise Price
Outstanding, beginning of year		6,630,934			1.30-6.00	$	2.66		6,480,934			1.30-6.00	$	2.68		5,864,626			1.30-6.00	$	2.69
Granted		—			—		—		—			—		—		—			—		—
Forfeited		(150,000	)		2.00	$	2.00		(616,308	)		1.90-3.44	$	2.58		(1,205,912	)		$1.63-2.87	$	1.95
Exercised		—			—		—		—			—		—		—			—		—
Outstanding, end of year		6,480,934			1.30-6.00	$	2.68		5,864,626			1.30-6.00	$	2.69		4,658,714			1.30-6.00	$	2.88
Exercisable, end of year		6,480,934			1.30-6.00	$	2.68		5,864,626			1.30-6.00	$	2.69		4,658,714			1.30-6.00	$	2.88
Weighted average remaining contractual life (years)		2-5 years							1-4 years							1-3 years
Available for future grants		170,019							—							—

2007 Equity Incentive Plans [Member]

Schedule of stock option activity

Information regarding the options approved by the Board of Directors under Equity Plan of 2007 is summarized below:

	2013						2014						2015
	Shares		Option Price		Weighted Average Exercise Price		Shares		Option Price		Weighted Average Exercise Price		Shares		Option Price		Weighted Average Exercise Price
Outstanding, beginning of year		1,550,000		0.72-3.05		2.17		1,550,000		0.72-3.05		2.17		1,550,000		0.72-3.05		2.17
Granted		—		—		—		—		—		—		—		—		—
Forfeited		—		—		—		—		—		—		—		—		—
Exercised		—		—		—		—		—		—		—		—		—
Outstanding, end of year		1,550,000		0.72-3.05		2.17		1,550,000		0.72-3.05		2.17		1,550,000		0.72-3.05		2.17
Exercisable, end of year		1,550,000		0.72-3.05		2.17		1,550,000		0.72-3.05		2.17		1,550,000		0.72-3.05		2.17
Weighted average remaining contractual life (years)		5-7 years						4-6 years						3-5 years
Available for future grants		3,004						3,004						3,004

2009 Equity Incentive Plans [Member]

Schedule of stock option activity

Information regarding the options approved by the Board of Directors under Equity Plan of 2009 is summarized below:

	2013						2014							2015
	Shares		Option Price		Weighted Average Exercise Price		Shares			Option Price		Weighted Average Exercise Price		Shares			Option Price		Weighted Average Exercise Price
Outstanding, beginning of year		4,688,978		0.21-4.03		0.61		6,708,978			0.21-4.03		0.61		7,673,262			0.21-4.03		0.55
Granted		2,020,000		0.22-2.00		0.40		1,314,284			0.33-2.60		0.40		800,000			0.25		0.25
Forfeited		—		—		—		(350,000	)		0.31-2.81		1.45		(653,728	)		0.25-4.03		1.74
Exercised		—		—		—		—			—		—		—			—		—
Outstanding, end of year		6,708,978		0.21-4.03		0.55		7,673,262			0.21-4.03		0.55		7,819,534			0.21-4.03		0.46
Exercisable, end of year		5,713,145		0.21-4.03		0.55		6,929,335			0.21-4.03		0.55		7,486,201			0.21-4.03		0.46
Weighted average remaining contractual life (years)		6-10 years						5-10 years							4-10 years
Available for future grants		3,090,478						1,487,543							8,341,271

Employees [Member]

Schedule of stock option activity

Stock option activity for employees: 

	Number of  Options			Weighted Average Exercise Price		Weighted Average Remaining Contracted Term (Years)		Aggregate Intrinsic Value
Outstanding December 31, 2012		9,441,480		$	1.90		5.35		—
Granted		1,170,000			0.36				—
Forfeited		—			—		—		—
Outstanding December 31, 2013		10,611,480		$	1.73		4.92		—
Granted		1,264,284			0.97		—		—
Forfeited		(587,876	)		1.78		—		—
Outstanding December 31, 2014		11,287,888		$	1.64		4.61		—
Granted		800,000			0.25		—		—
Forfeited		(1,362,640	)		1.31		—		—
Outstanding December 31, 2015		10,725,248		$	1.58		4.02		—
Vested and expected to vest at December 31, 2015		10,391,915		$	1.54		3.73		—
Exercisable at December 31, 2015		10,391,915		$	1.54		3.73		—

Schedule of unvested stock option

Unvested stock option activity for employees:

	Number of  Options			Weighted  Average Exercise  Price		Average  Remaining  Contracted  Term (Years)		Aggregate Intrinsic  Value
Outstanding December 31, 2012		516,373		$	0.45		9.43		—
Granted		595,000			0.24		—		—
Vested		(586,373	)		0.38		—		—
Forfeited		—			—		—		—
Outstanding December 31, 2013		525,000		$	0.29		8.38		—
Granted		1,264,284			0.97		—		—
Vested		(1,078,690	)		0.38		—		—
Forfeited		—			—		—		—
Outstanding December 31, 2014		710,594		$	1.38		8.76		—
Granted		800,000			0.25		—		—
Vested		(1,177,261	)		0.92		—		—
Forfeited		—			—		—		—
Outstanding December 31, 2015		333,333		$	0.29		7.82		—

Non-Employees [Member]

Schedule of stock option activity

Stock option activity for non-employees during the year:

	Number of  Options			Weighted  Average Exercise  Price		Weighted  Average  Remaining  Contracted  Term (Years)		Aggregate Intrinsic Value
Outstanding December 31, 2012		3,428,432		$	1.73		4.71		—
Granted		850,000			0.56		—		—
Exercised		—			—		—		—
Forfeited		(150,000	)		2.00		—		—
Outstanding December 31, 2013		4,128,432		$	1.48		5.01		—
Granted		50,000			2.60		—		—
Exercised		—			—		—		—
Forfeited		(378,432	)		2.78		—		—
Outstanding December 31, 2014		3,800,000		$	1.36		4.75		—
Granted		—			—		—		—
Exercised		—			—		—		—
Forfeited		(497,000	)		1.86		—		—
Outstanding December 31, 2015		3,303,000		$	1.29		4.31		—
Vested and expected to vest at December 31, 2015		3,303,000		$	1.29		4.31		—
Exercisable at December 31, 2015		3,303,000		$	1.29		4.31		—

Schedule of unvested stock option

Unvested stock option activity for non-employees:

	Number of Options			Weighted Average Exercise Price		Weighted Average Remaining Contracted Term (Years)		Aggregate Intrinsic Value
Outstanding December 31, 2012		210,422		$	0.40		9.68		—
Granted		470,833			0.25		—		—
Vested		(210,422	)		0.40		—		—
Forfeited		—			—		—		—
Outstanding December 31, 2013		470,833		$	0.25		9.61		—
Granted		50,000			2.60		—		—
Vested		(487,500	)		0.33		—		—
Forfeited		—			—		—		—
Outstanding December 31, 2014		33,333		$	2.60		9.08		—
Granted		—			—		—		—
Vested		(33,333	)		2.60		—		—
Forfeited		—			—		—		—
Outstanding December 31, 2015		—		$	—		—		—