Stockholders’ Equity (Details Narrative) - USD ($)									1 Months Ended	3 Months Ended			12 Months Ended
	Apr. 19, 2023	Jul. 07, 2020	Mar. 31, 2020	Sep. 27, 2019	Jan. 28, 2019	Nov. 14, 2018	Oct. 17, 2018	Sep. 12, 2018	Aug. 31, 2020	Mar. 31, 2023	Mar. 31, 2022	Dec. 31, 2021	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Class of Stock [Line Items]
Common stock, shares authorized										350,000,000			350,000,000
Common stock specific limitations and restrictions on usage										8,000,000
Common stock shares issued, value	$ 485									$ 100,000
Number of shares issued upon transaction										969
Proceeds from Issuance or Sale of Equity										$ 100,000
Warrant gross proceeds			$ 264,000
Warrant modification			$ 46,000
Warrant outstanding										15,000
Number of options granted										0	150,000
Common stock, shares outstanding										48,407,326			48,084,287
2018 Equity Incentive Plan [Member]
Class of Stock [Line Items]
Number of stock is reserved for potential issuance								7,000,000
Option vested years							10 years
Number of options granted							26,324
Option exercise price per share							$ 9.68
Pre-Funded Warrants [Member]
Class of Stock [Line Items]
Exercise price				$ 0.001
Shares issued price per share				$ 0.899
Percentage of outstanding stock				4.99%
Pre-funded warrants exercised															1,870,000
Warrant [Member]
Class of Stock [Line Items]
Exercise price				$ 0.99
Pre-funded warrants exercised															8,873,960
Alliance Global Partners, LLC [Member]
Class of Stock [Line Items]
Number of shares issued upon transaction				1,740,550
Warrants issued				7,148,310
Proceeds from Issuance or Sale of Equity				$ 7,200,000
Alliance Global Partners, LLC [Member] | Warrants [Member]
Class of Stock [Line Items]
Warrants exercised aggregate				8,888,860
Alliance Global Partners, LLC [Member] | Pre-Funded Warrants [Member]
Class of Stock [Line Items]
Shares issued price per share				$ 0.90
Maximum [Member] | Alliance Global Partners, LLC [Member] | Representative Warrants [Member]
Class of Stock [Line Items]
Warrants exercised aggregate			266,665	266,665
Directors, Officers and Employees [Member]
Class of Stock [Line Items]
Common stock shares issued, value		$ 500,000
Rights [Member]
Class of Stock [Line Items]
Exercise price										$ 1,000
Proceeds from warrants										$ 4,700,000
Warrant [Member]
Class of Stock [Line Items]
Exercise price										$ 8.80
Warrants and rights outstanding term										5 years
Series A Junior Participating Preferred Stock [Member]
Class of Stock [Line Items]
Preferred stock, shares authorized										250,000
Series B Convertible Preferred Stock [Member]
Class of Stock [Line Items]
Preferred stock, shares authorized										8,000
Preferred stock stated value										$ 1,000			$ 1,000
Preferred Stock, no par value										$ 0
Preferred stock, shares outstanding										692			696
Conversion of common stock										0
Series B Convertible Preferred Stock [Member] | Rights [Member]
Class of Stock [Line Items]
Preferred stock face value										$ 1,000
Preferred Stock [Member]
Class of Stock [Line Items]
Number of shares to be issued on conversion										114
Common Stock [Member]
Class of Stock [Line Items]
Common stock shares issued, value										$ 100,000			$ 205,000
Number of shares issued upon transaction										322,583			132,238	86,817
Shares issued price per share										$ 0.31
Common Stock [Member] | Minimum [Member]
Class of Stock [Line Items]
Shares issued price per share												$ 0.76	$ 1.16	$ 0.76
Common Stock [Member] | Maximum [Member]
Class of Stock [Line Items]
Shares issued price per share												$ 1.02	$ 2.35	$ 1.02
Board Of Directors [Member]
Class of Stock [Line Items]
Preferred stock, shares authorized										5,000,000
Preferred stock stated value										$ 0.01
Director [Member]
Class of Stock [Line Items]
Option vested years								10 years
Employees [Member] | 2018 Equity Incentive Plan [Member]
Class of Stock [Line Items]
Number of options granted						23
Option exercise price per share						$ 9.68
Officers [Member] | 2018 Equity Incentive Plan [Member]
Class of Stock [Line Items]
Number of options granted					27,570				400,000
Option exercise price per share					$ 9.68
Expiration period					10 years				10 years
Officers [Member] | Minimum [Member] | 2018 Equity Incentive Plan [Member]
Class of Stock [Line Items]
Option exercise price per share									$ 2.77
Officers [Member] | Maximum [Member] | 2018 Equity Incentive Plan [Member]
Class of Stock [Line Items]
Option exercise price per share									$ 3.07
Employees [Member] | 2018 Equity Incentive Plan [Member]
Class of Stock [Line Items]
Number of options granted												613,512	850,000
Expiration period												10 years	10 years
Employees [Member] | Minimum [Member] | 2018 Equity Incentive Plan [Member]
Class of Stock [Line Items]
Number of options granted													0.31
Option exercise price per share												$ 1.11
Employees [Member] | Maximum [Member] | 2018 Equity Incentive Plan [Member]
Class of Stock [Line Items]
Option exercise price per share												$ 1.71	$ 1.71