Schedule of Stock Option Activity (Details) - $ / shares	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
2009 Equity Incentive Plans [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Number of options outstanding, beginning of year	128,504	129,680
Weighted average exercise price outstanding, beginning of year	$ 25.58	$ 23.05
Number of options, granted
Weighted average exercise price, granted
Number of options, forfeited	(4,105)	(1,176)
Weighted average exercise price, forfeited	$ 129.88	$ 289.62
Number of options, exercised
Option price, exercised
Weighted average exercise price, exercised
Number of options outstanding, ending of year	124.399	128,504
Weighted average exercise price outstanding, end of year	$ 22.23	$ 25.58
Number of options outstanding, end of year	124,399	126,393
Weighted average remaining contractual life (years)	5 years 11 months 23 days	5 years 10 months 24 days
2009 Equity Incentive Plans [Member] | Minimum [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Option price outstanding, beginning of year	$ 13.20	$ 13.20
Option price, forfeited	16.76	16.76
Option price outstanding, end of year	13.20	13.20
Option price exercisable, end of year	13.20	13.20
2009 Equity Incentive Plans [Member] | Maximum [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Option price outstanding, beginning of year	2,127.84	2,127.84
Option price, forfeited	2,127.84	1,056.00
Option price outstanding, end of year	1,003.20	2,127.84
Option price exercisable, end of year	$ 1,003.20	$ 2,127.84
2018 Equity Incentive Plans [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Number of options outstanding, beginning of year	1,650,017	1,086,549
Weighted average exercise price outstanding, beginning of year	$ 2.35	$ 2.75
Number of options, granted	850,000	613,512
Weighted average exercise price, granted	$ 0.51	$ 1.67
Number of options, forfeited	(25,046)	(50,044)
Weighted average exercise price, forfeited	$ 1.86	$ 1.86
Number of options, exercised
Option price, exercised
Weighted average exercise price, exercised
Number of options outstanding, ending of year	2,474,971	1,650,017
Weighted average exercise price outstanding, end of year	$ 1.72	$ 2.35
Number of options outstanding, end of year	1,916,637	1,141,798
Weighted average remaining contractual life (years)	9 years 7 months 24 days	9 years 1 month 13 days
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price	$ 2.22	$ 2.35
Number of options outstanding, beginning of year	466,120	344,322
2018 Equity Incentive Plans [Member] | Minimum [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Option price outstanding, beginning of year	$ 1.11	$ 1.85
Option price, forfeited	1.85	1.85
Option price outstanding, end of year	0.31	1.11
Option price exercisable, end of year	0.41	1.11
Option price, granted	0.31	1.11
2018 Equity Incentive Plans [Member] | Maximum [Member]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Option price outstanding, beginning of year	9.68	9.68
Option price, forfeited	9.68	8.50
Option price outstanding, end of year	9.68	9.68
Option price exercisable, end of year	9.68	9.68
Option price, granted	$ 1.71	$ 1.71