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Stockholders’ Equity (Details Narrative) - USD ($)
3 Months Ended 9 Months Ended 12 Months Ended
Jul. 07, 2020
Sep. 27, 2019
Sep. 12, 2018
Sep. 30, 2022
Jun. 30, 2022
Mar. 31, 2022
Dec. 31, 2021
Sep. 30, 2021
Mar. 31, 2021
Sep. 30, 2022
Sep. 30, 2021
Dec. 31, 2021
Dec. 31, 2020
Mar. 16, 2018
Class of Stock [Line Items]                            
Preferred stock, shares authorized       5,000,000           5,000,000        
Preferred stock stated value       $ 0.01           $ 0.01        
Warrant exercise price                           $ 17.05
Warrants and rights outstanding term                           5 years
Common stock, shares authorized       350,000,000     350,000,000     350,000,000   350,000,000    
Common stock specific limitations and restrictions on usage       8,000,000           8,000,000        
Common stock shares issued, value       $ 25,000 $ 55,000     $ 30,000 $ 12,887,000          
Warrants issued                           73,314
Proceeds from Issuance or Sale of Equity                   $ 80,000 $ 12,917,000      
Warrant outstanding       15,000           15,000        
Number of options granted                   300,000 0      
Common stock, shares outstanding       48,082,275     47,994,672     48,082,275   47,994,672    
Director [Member]                            
Class of Stock [Line Items]                            
Option vested years     10 years                      
2018 Equity Incentive Plan [Member]                            
Class of Stock [Line Items]                            
Number of stock is reserved for potential issuance     7,000,000                      
2018 Equity Incentive Plan [Member] | Employees [Member]                            
Class of Stock [Line Items]                            
Number of options granted           300,000 613,512              
Option exercise price per share           $ 0.70                
Expiration period           10 years 10 years              
Pre-Funded Warrants [Member]                            
Class of Stock [Line Items]                            
Shares issued price per share   $ 0.899                        
Percentage of outstanding stock   4.99%                        
Warrant [Member]                            
Class of Stock [Line Items]                            
Warrant exercise price   $ 0.99                        
Alliance Global Partners, LLC [Member]                            
Class of Stock [Line Items]                            
Number of shares issued upon transaction   1,740,550                        
Warrants issued   7,148,310                        
Proceeds from Issuance or Sale of Equity   $ 7,200,000                        
Alliance Global Partners, LLC [Member] | Warrants [Member]                            
Class of Stock [Line Items]                            
Number of warrant to purchase shares of common stock   8,888,860                        
Alliance Global Partners, LLC [Member] | Pre-Funded Warrants [Member]                            
Class of Stock [Line Items]                            
Shares issued price per share   $ 0.90                        
Maxim Group LLC [Member] | Equity Distribution Agreement [Member]                            
Class of Stock [Line Items]                            
Proceeds from Issuance or Sale of Equity                       $ 13,301,526 $ 53,936,615  
Sale of stock, Number of shares issued                       5,665,731 20,444,807  
Shares sales fee percentage             3.50%         3.50% 3.50%  
Underwriting fee amount.                       $ 465,533 $ 1,888,727  
Minimum [Member] | 2018 Equity Incentive Plan [Member] | Employees [Member]                            
Class of Stock [Line Items]                            
Option exercise price per share             $ 1.11              
Maximum [Member] | 2018 Equity Incentive Plan [Member] | Employees [Member]                            
Class of Stock [Line Items]                            
Option exercise price per share             1.71              
Maximum [Member] | Alliance Global Partners, LLC [Member] | Representative Warrants [Member]                            
Class of Stock [Line Items]                            
Number of warrant to purchase shares of common stock   266,665                        
Directors, Officers and Employees [Member]                            
Class of Stock [Line Items]                            
Common stock shares issued, value $ 500,000                          
Rights [Member]                            
Class of Stock [Line Items]                            
Warrant exercise price       $ 1,000           $ 1,000        
Proceeds from warrants                   $ 4,700,000        
Warrant [Member]                            
Class of Stock [Line Items]                            
Warrant exercise price       $ 8.80           $ 8.80        
Warrants and rights outstanding term       5 years           5 years        
Series A Junior Participating Preferred Stock [Member]                            
Class of Stock [Line Items]                            
Preferred stock, shares authorized       250,000           250,000        
Series B Convertible Preferred Stock [Member]                            
Class of Stock [Line Items]                            
Preferred stock, shares authorized       8,000           8,000        
Preferred stock stated value       $ 1,000     $ 1,000     $ 1,000   $ 1,000    
Preferred Stock, no par value       $ 0           $ 0        
Preferred Stock, Shares Outstanding       713     715     713   715    
Conversion of common stock                   2 7      
Series B Convertible Preferred Stock [Member] | Rights [Member]                            
Class of Stock [Line Items]                            
Preferred stock face value       $ 1,000           $ 1,000        
Preferred Stock [Member]                            
Class of Stock [Line Items]                            
Number of shares to be issued on conversion       114           114        
Common Stock [Member]                            
Class of Stock [Line Items]                            
Common stock shares issued, value                   $ 80,000   $ 205,000    
Number of shares issued upon transaction                   87,045   132,238    
Common Stock [Member] | Minimum [Member]                            
Class of Stock [Line Items]                            
Shares issued price per share       $ 0.76     $ 1.16     $ 0.76   $ 1.16    
Common Stock [Member] | Maximum [Member]                            
Class of Stock [Line Items]                            
Shares issued price per share       $ 1.02     $ 2.35     $ 1.02   $ 2.35