Schedule of Warrants Outstanding and Exercisable (Details) - Warrant [Member] - $ / shares	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Accumulated Other Comprehensive Income (Loss) [Line Items]
Number of options outstanding, beginning of year	375,100	10,201,761
Weighted average exercise price outstanding, beginning of year	$ 116.38	$ 1.54
Number of options, granted
Warrant price, granted
Weighted average exercise price, granted
Number of options, expired	(79,593)
Warrant price, expired
Weighted average exercise price, expired	$ 20.85
Number of options, exercised	(568)	(9,826,661)
Warrant price, exercised	$ 8.80
Weighted average exercise price, exercised	$ 8.80	$ 0.97
Number of options outstanding, ending of year	294,939	375,100
Weighted average exercise price outstanding, ending of year	$ 15.19	$ 116.38
Number of options exercisable, end of year	294,939	375,100
Weighted average exercise price exercisable, end of year	$ 15.19	$ 116.38
Weighted average remaining contracted term (years) outstanding, ending of year	4 years 9 months	5 years 9 months
Minimum [Member]
Accumulated Other Comprehensive Income (Loss) [Line Items]
Warrant price outstanding, beginning of year	$ 0.99	$ 0.99
Warrant price, expired	17.16
Warrant price, exercised		0.90
Warrant price outstanding, end of year	0.99	0.99
Warrant price exercisable, end of year	$ 0.99	$ 0.99
Years exercisable	2022	2021
Maximum [Member]
Accumulated Other Comprehensive Income (Loss) [Line Items]
Warrant price outstanding, beginning of year	$ 469.92	$ 469.92
Warrant price, expired	84.48
Warrant price, exercised		8.80
Warrant price outstanding, end of year	469.92	469.92
Warrant price exercisable, end of year	$ 469.92	$ 469.92
Years exercisable	2025	2024