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Stockholders’ Equity (Details Narrative) - USD ($)
1 Months Ended 3 Months Ended 9 Months Ended 12 Months Ended
Jul. 12, 2020
Jul. 07, 2020
Sep. 27, 2019
Jan. 28, 2019
Nov. 14, 2018
Oct. 17, 2018
Sep. 12, 2018
Dec. 31, 2020
Aug. 31, 2020
Sep. 30, 2021
Mar. 31, 2021
Sep. 30, 2020
Jun. 30, 2020
Mar. 31, 2020
Sep. 30, 2021
Dec. 31, 2020
Mar. 16, 2018
Class of Stock [Line Items]                                  
Preferred stock, shares authorized                   5,000,000         5,000,000    
Preferred stock stated value                   $ 0.01         $ 0.01    
Subscription/exercise price                                 $ 17.05
Preferred stock conversion price                   $ 8.80         $ 8.80    
Warrants and Rights Outstanding, Term                                 5 years
Common stock, shares authorized               350,000,000   350,000,000         350,000,000 350,000,000  
Common stock shares with specific limitations and restrictions on usage                   8,000,000         8,000,000    
Common stock shares issued, value                   $ 30,000 $ 12,887,000 $ 17,241,000 $ 15,016,000 $ 25,764,000      
Number of shares issuable upon exercise of warrant                                 73,314
Proceeds from Warrant Exercises                             $ 264,000,000    
Warrant modification.                             $ 46,000,000    
Common stock, shares outstanding               42,154,371   47,848,622         47,848,622 42,154,371  
2018 Equity Incentive Plan [Member]                                  
Class of Stock [Line Items]                                  
Number of stock is reserved for potential issuance             7,000,000                    
Expiration period           10 years 10 years                    
Number of options issued           26,324                      
Exercise price           $ 9.68                      
2018 Equity Incentive Plan [Member] | Employees [Member]                                  
Class of Stock [Line Items]                                  
Expiration period         10 years                        
Number of options issued         23                        
Exercise price         $ 9.68                        
2018 Equity Incentive Plan [Member] | Officers [Member]                                  
Class of Stock [Line Items]                                  
Expiration period       10 years         10 years                
Number of options issued       27,570         400,000                
Exercise price       $ 9.68                          
Vesting period       1 year         1 year                
2018 Equity Incentive Plan [Member] | Employees [Member]                                  
Class of Stock [Line Items]                                  
Expiration period               10 years                  
Number of options issued               675,000                  
Vesting period               1 year                  
Equity Distribution Agreement [Member]                                  
Class of Stock [Line Items]                                  
Sale of Stock, Number of Shares Issued in Transaction                             5,665,731    
Pre-funded Warrants [Member]                                  
Class of Stock [Line Items]                                  
Number of warrants exercised                             1,870,000    
Warrant [Member]                                  
Class of Stock [Line Items]                                  
Number of warrants exercised                             7,687,860    
Alliance Global Partners, LLC [Member]                                  
Class of Stock [Line Items]                                  
Number of shares issued upon transaction     1,740,550                            
Number of shares issuable upon exercise of warrant     7,148,310                            
Proceeds from issuance of secuirites     $ 7,200,000,000                            
Alliance Global Partners, LLC [Member] | Warrants [Member]                                  
Class of Stock [Line Items]                                  
Number of warrant to purchase shares of common stock     8,888,860                            
Alliance Global Partners, LLC [Member] | Pre-funded Warrants [Member]                                  
Class of Stock [Line Items]                                  
Shares issued price per share     $ 0.90                            
Maxim Group LLC [Member] | Equity Distribution Agreement [Member]                                  
Class of Stock [Line Items]                                  
Proceeds from issuance of secuirites                             $ 13,301,526 $ 53,936,615  
Sale of Stock, Number of Shares Issued in Transaction                               20,444,807  
Shares sales fee percentage               3.50%   3.50%         3.50% 3.50%  
Underwriting fee amount.                             $ 465,533 $ 1,888,727  
Minimum [Member] | 2018 Equity Incentive Plan [Member] | Officers [Member]                                  
Class of Stock [Line Items]                                  
Exercise price                 $ 2.77                
Minimum [Member] | 2018 Equity Incentive Plan [Member] | Employees [Member]                                  
Class of Stock [Line Items]                                  
Exercise price               $ 1.85                  
Maximum [Member] | 2018 Equity Incentive Plan [Member] | Officers [Member]                                  
Class of Stock [Line Items]                                  
Exercise price                 $ 3.07                
Maximum [Member] | 2018 Equity Incentive Plan [Member] | Employees [Member]                                  
Class of Stock [Line Items]                                  
Exercise price               1.96                  
Maximum [Member] | Alliance Global Partners, LLC [Member] | Representative Warrants [Member]                                  
Class of Stock [Line Items]                                  
Number of warrant to purchase shares of common stock     266,665                            
Directors, Officers and Employees [Member]                                  
Class of Stock [Line Items]                                  
Common stock shares issued, value $ 500,000 $ 500,000                              
Rights [Member]                                  
Class of Stock [Line Items]                                  
Subscription/exercise price                   $ 1,000         $ 1,000    
Proceeds from warrants                             $ 4,700,000    
Warrant [Member]                                  
Class of Stock [Line Items]                                  
Subscription/exercise price                   $ 8.80         $ 8.80    
Warrants and Rights Outstanding, Term                   5 years         5 years    
Series A Junior Participating Preferred Stock [Member]                                  
Class of Stock [Line Items]                                  
Preferred stock, shares authorized                   250,000         250,000    
Series B Convertible Preferred Stock [Member]                                  
Class of Stock [Line Items]                                  
Preferred stock, shares authorized                   8,000         8,000    
Preferred stock stated value               $ 1,000   $ 1,000         $ 1,000 $ 1,000  
Preferred Stock, No Par Value                   $ 0         $ 0    
Preferred stock, shares authorized               732   732         732 732  
Series B Convertible Preferred Stock [Member] | Rights [Member]                                  
Class of Stock [Line Items]                                  
Preferred stock value                   $ 1,000         $ 1,000    
Series B Convertible Preferred Stocks [Member]                                  
Class of Stock [Line Items]                                  
Preferred stock, shares authorized                   725         725    
Preferred Stock [Member]                                  
Class of Stock [Line Items]                                  
Number of shares to be issued on conversion                   114         114    
Common Stock [Member]                                  
Class of Stock [Line Items]                                  
Common stock shares issued, value   $ 25,000                         $ 80,000 $ 50,000  
Number of shares issued upon transaction   10,730                         37,325 27,501  
Shares issued price per share   $ 2.33                              
Common Stock [Member] | Minimum [Member]                                  
Class of Stock [Line Items]                                  
Shares issued price per share               $ 1.72   $ 1.92         $ 1.92 $ 1.72  
Common Stock [Member] | Maximum [Member]                                  
Class of Stock [Line Items]                                  
Shares issued price per share               $ 2.03   $ 2.35         $ 2.35 $ 2.03