<SEC-DOCUMENT>0001493152-19-001474-index.html : 20190206
<SEC-HEADER>0001493152-19-001474.hdr.sgml : 20190206
<ACCEPTANCE-DATETIME>20190206170405
ACCESSION NUMBER:		0001493152-19-001474
CONFORMED SUBMISSION TYPE:	S-1/A
PUBLIC DOCUMENT COUNT:		19
FILED AS OF DATE:		20190206
DATE AS OF CHANGE:		20190206

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			HEMISPHERX BIOPHARMA INC
		CENTRAL INDEX KEY:			0000946644
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				520845822
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-1/A
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-229051
		FILM NUMBER:		19572209

	BUSINESS ADDRESS:	
		STREET 1:		2117 SW HIGHWAY 484
		CITY:			OCALA
		STATE:			FL
		ZIP:			32801
		BUSINESS PHONE:		215-988-0080

	MAIL ADDRESS:	
		STREET 1:		2117 SW HIGHWAY 484
		CITY:			OCALA
		STATE:			FL
		ZIP:			32801
</SEC-HEADER>
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<TYPE>S-1/A
<SEQUENCE>1
<FILENAME>forms-1a.htm
<TEXT>
Document 1 - file: forms-1a.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-1.1
<SEQUENCE>2
<FILENAME>ex1-1.htm
<TEXT>
Document 2 - file: ex1-1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-3.5
<SEQUENCE>3
<FILENAME>ex3-5.htm
<TEXT>
Document 3 - file: ex3-5.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.14
<SEQUENCE>4
<FILENAME>ex4-14.htm
<TEXT>
Document 4 - file: ex4-14.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.15
<SEQUENCE>5
<FILENAME>ex4-15.htm
<TEXT>
Document 5 - file: ex4-15.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-16
<SEQUENCE>6
<FILENAME>ex4-16.htm
<TEXT>
Document 6 - file: ex4-16.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>7
<FILENAME>ex5-1.htm
<TEXT>
Document 7 - file: ex5-1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-8.1
<SEQUENCE>8
<FILENAME>ex8-1.htm
<TEXT>
Document 8 - file: ex8-1.htm

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<DOCUMENT>
<TYPE>EX-23.1
<SEQUENCE>9
<FILENAME>ex23-1.htm
<TEXT>
Document 9 - file: ex23-1.htm

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<DOCUMENT>
<TYPE>EX-99.1
<SEQUENCE>10
<FILENAME>ex99-1.htm
<TEXT>
Document 10 - file: ex99-1.htm

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<DOCUMENT>
<TYPE>EX-99.2
<SEQUENCE>11
<FILENAME>ex99-2.htm
<TEXT>
Document 11 - file: ex99-2.htm

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<DOCUMENT>
<TYPE>EX-99.3
<SEQUENCE>12
<FILENAME>ex99-3.htm
<TEXT>
Document 12 - file: ex99-3.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.4
<SEQUENCE>13
<FILENAME>ex99-4.htm
<TEXT>
Document 13 - file: ex99-4.htm

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<DOCUMENT>
<TYPE>EX-99.5
<SEQUENCE>14
<FILENAME>ex99-5.htm
<TEXT>
Document 14 - file: ex99-5.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.6
<SEQUENCE>15
<FILENAME>ex99-6.htm
<TEXT>
Document 15 - file: ex99-6.htm

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<DOCUMENT>
<TYPE>EX-99.7
<SEQUENCE>16
<FILENAME>ex99-7.htm
<TEXT>
Document 16 - file: ex99-7.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>17
<FILENAME>ex4-14_001.jpg
<TEXT>
Document 17 - file: ex4-14_001.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>18
<FILENAME>ex4-14_002.jpg
<TEXT>
Document 18 - file: ex4-14_002.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>19
<FILENAME>ex8-1_001.jpg
<TEXT>
Document 19 - file: ex8-1_001.jpg

</DOCUMENT>
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