<SEC-DOCUMENT>0001493152-18-009595-index.html : 20180703
<SEC-HEADER>0001493152-18-009595.hdr.sgml : 20180703
<ACCEPTANCE-DATETIME>20180703084028
ACCESSION NUMBER:		0001493152-18-009595
CONFORMED SUBMISSION TYPE:	S-3
PUBLIC DOCUMENT COUNT:		4
FILED AS OF DATE:		20180702
DATE AS OF CHANGE:		20180703

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			HEMISPHERX BIOPHARMA INC
		CENTRAL INDEX KEY:			0000946644
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				520845822
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-3
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-226059
		FILM NUMBER:		18934775

	BUSINESS ADDRESS:	
		STREET 1:		860 N. ORANGE AVENUE
		STREET 2:		SUITE B
		CITY:			ORLANDO
		STATE:			FL
		ZIP:			32801
		BUSINESS PHONE:		407-271-8516

	MAIL ADDRESS:	
		STREET 1:		860 N. ORANGE AVENUE
		STREET 2:		SUITE B
		CITY:			ORLANDO
		STATE:			FL
		ZIP:			32801
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-3
<SEQUENCE>1
<FILENAME>forms-3.htm
<TEXT>
Document 1 - file: forms-3.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-4.13
<SEQUENCE>2
<FILENAME>ex4-13.htm
<TEXT>
Document 2 - file: ex4-13.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>3
<FILENAME>ex5-1.htm
<TEXT>
Document 3 - file: ex5-1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.1
<SEQUENCE>4
<FILENAME>ex23-1.htm
<TEXT>
Document 4 - file: ex23-1.htm

</DOCUMENT>
</SEC-DOCUMENT>