<SEC-DOCUMENT>0000946644-15-000023-index.html : 20150625
<SEC-HEADER>0000946644-15-000023.hdr.sgml : 20150625
<ACCEPTANCE-DATETIME>20150625161009
ACCESSION NUMBER:		0000946644-15-000023
CONFORMED SUBMISSION TYPE:	S-3
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20150625
DATE AS OF CHANGE:		20150625

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			HEMISPHERX BIOPHARMA INC
		CENTRAL INDEX KEY:			0000946644
		STANDARD INDUSTRIAL CLASSIFICATION:	BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836]
		IRS NUMBER:				520845822
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-3
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-205228
		FILM NUMBER:		15951927

	BUSINESS ADDRESS:	
		STREET 1:		1617 JFK BLVD, SUITE #500
		STREET 2:		ONE PENN CENTER
		CITY:			PHILADELPHIA
		STATE:			PA
		ZIP:			19103
		BUSINESS PHONE:		215-988-0080

	MAIL ADDRESS:	
		STREET 1:		1617 JFK BLVD, SUITE #500
		STREET 2:		ONE PENN CENTER
		CITY:			PHILADELPHIA
		STATE:			PA
		ZIP:			19103
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-3
<SEQUENCE>1
<FILENAME>s-3universalshelf6x24x15fi.htm
<DESCRIPTION>S-3
<TEXT>
Document 1 - file: s-3universalshelf6x24x15fi.htm

</DOCUMENT>
</SEC-DOCUMENT>