Note 5 - Fair Value Measurements - Assets Measured at Fair Value on a Non-recurring Basis (Details) - Fair Value, Nonrecurring [Member] - USD ($) $ in Thousands	Mar. 31, 2023	Dec. 31, 2022
Goodwill	$ 2,574
Rostafuroxin Drug Candidate [Member]
Goodwill		$ 3,058
Rostafuroxin drug candidate		2,910
Fair Value, Inputs, Level 1 [Member]
Goodwill	0
Fair Value, Inputs, Level 2 [Member]
Goodwill	0
Fair Value, Inputs, Level 3 [Member]
Goodwill	$ 2,574
Fair Value, Inputs, Level 3 [Member] | Rostafuroxin Drug Candidate [Member]
Goodwill		3,058
Rostafuroxin drug candidate		$ 2,910