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Note 4 - Summary of Significant Accounting Policies (Tables)
3 Months Ended
Mar. 31, 2019
Notes Tables  
Schedule of Indefinite-Lived Intangible Assets [Table Text Block]
(in thousands)
 
Estimated Fair
Value
 
         
Istaroxime drug candidate
  $
22,340
 
Rostafuroxin drug candidate
   
54,750
 
Total
  $
77,090