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Note 7 - Long-term Debt (Tables)
6 Months Ended
Jun. 30, 2017
Notes Tables  
Schedule of Long-term Debt Instruments [Table Text Block]
   
June 30,
   
December 31,
 
(in thousands)
 
2017
   
2016
 
                 
Current portion
  $
12,500
    $
-
 
Non-current portion
   
12,500
     
25,000
 
Total Deerfield Loan
  $
25,000
    $
25,000
 
Schedule of Debt Instrument Interest Expense [Table Text Block]
   
Three Months Ended
June 30,
   
Six Months Ended
June 30,
 
(in thousands)
 
2017
   
2016
   
2017
   
2016
 
                                 
Amortization of prepaid interest expense
  $
273
    $
544
    $
543
    $
1,088
 
Cash interest expense
   
257
     
-
     
511
     
-
 
Total interest expense
  $
530
    $
544
    $
1,054
    $
1,088