Exhibit 31.4

CERTIFICATIONS

I, John G. Cooper, certify that:

1.           I have reviewed this Amendment No. 1 on Form 10-K/A for the fiscal year ended December 31, 2010 of Discovery Laboratories, Inc.; and

2.           Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report.

Date:  April 29, 2011	/s/ John G. Cooper
	John G. Cooper
	President and Chief Financial Officer