<DOCUMENT>
<TYPE>EX-2.1
<SEQUENCE>4
<FILENAME>ex2-1tosch13ga_112002.txt
<DESCRIPTION>EXH. 2.1 TO SCH. 13G/A FOR DISCOVERY LAB
<TEXT>
      EX-2.1 OTHERDOC
      Statement of Control Person

                                                                    Exhibit 2.1
                                                                    ----------

                             STATEMENT OF CONTROL PERSON


The Statement on this Schedule 13G/A dated November 21, 2002 with respect to the
common stock par value $0.001 per share of Discovery Laboratories, Inc. is filed
by Samuel D. Isaly in accordance with the provisions of Rule 13d-1(c) and Rule
13d-1(k) respectively as a control person (HC) of Orbimed Advisors LLC and
Orbimed Advisors Inc.

Orbimed Advisors Inc. and OrbiMed Advisors LLC file this statement on Schedule
13G/A in accordance with the provisions of Rule 13d-1(b) and Rule 13d-1(k)
respectively as investment advisors (IA).


</TEXT>
</DOCUMENT>