CONDENSED CONSOLIDATED BALANCE SHEETS - USD ($) $ in Thousands	Sep. 30, 2022	Dec. 31, 2021
Current assets:
Cash and cash equivalents	$ 180,838	$ 134,710
Accounts receivable, net	123,188	259,637
Inventory, net	71,429	86,502
Other current assets and prepaid expenses	38,516	27,170
Assets held for sale	0	314,994
Total current assets	413,971	823,013
Property, plant and equipment, net	79,949	79,727
Intangible assets, net	835,136	321,683
In-process research and development	195,000	590,200
Goodwill	573,499	520,601
Investments	77,804	10,729
Operating lease right-of-use assets	39,790	44,228
Other assets	9,636	9,534
Total assets	2,224,785	2,399,715
Current liabilities:
Accounts payable	49,748	82,040
Accrued expenses	112,015	193,493
Current maturities of operating leases	11,535	11,624
Current portion of convertible notes	70,632	0
Liabilities associated with assets held-for-sale	0	28,156
Current portion of lines of credit and notes payable	23,342	14,695
Total current liabilities	267,272	330,008
Operating lease liabilities	29,005	33,097
Long term portion of convertible notes	141,815	187,935
Deferred tax liabilities	135,073	148,487
Other long-term liabilities, principally contract liabilities, contingent consideration and lines of credit	22,552	15,062
Total long-term liabilities	328,445	384,581
Total liabilities	595,717	714,589
Equity:
Common Stock - $0.01 par value, 1,000,000,000 shares authorized; 781,341,231 and 690,082,283 shares issued at September 30, 2022 and December 31, 2021, respectively	7,814	6,901
Treasury Stock - 8,655,082 shares at September 30, 2022 and December 31, 2021, respectively	(1,791)	(1,791)
Additional paid-in capital	3,418,763	3,222,487
Accumulated other comprehensive loss	(58,026)	(30,495)
Accumulated deficit	(1,737,692)	(1,511,976)
Total shareholders’ equity	1,629,068	1,685,126
Total liabilities and equity	$ 2,224,785	$ 2,399,715