Equity Security, FV-NI, Ownership Percentage

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Operating Leases, Monthly Payments, Year Five

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Operating Leases, Monthly Payments, Year One

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Related Party Transaction, Future Contribution, Term

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Related Party Transaction, Future Contributions

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Related Party Transaction, Shares

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Area of a real estate property.

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- Definition

The percentage of ownership of common stock or equity participation in the investee accounted for under the equity method of accounting.

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- Definition

The carrying value as of the balance sheet date of the current and noncurrent portions of long-term obligations drawn from a line of credit, which is a bank's commitment to make loans up to a specific amount. Examples of items that might be included in the application of this element may consist of letters of credit, standby letters of credit, and revolving credit arrangements, under which borrowings can be made up to a maximum amount as of any point in time conditional on satisfaction of specified terms before, as of and after the date of drawdowns on the line. Includes short-term obligations that would normally be classified as current liabilities but for which (a) postbalance sheet date issuance of a long term obligation to refinance the short term obligation on a long term basis, or (b) the enterprise has entered into a financing agreement that clearly permits the enterprise to refinance the short-term obligation on a long term basis and the following conditions are met (1) the agreement does not expire within 1 year and is not cancelable by the lender except for violation of an objectively determinable provision, (2) no violation exists at the BS date, and (3) the lender has entered into the financing agreement is expected to be financially capable of honoring the agreement.

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- Definition

Maximum borrowing capacity under the credit facility without consideration of any current restrictions on the amount that could be borrowed or the amounts currently outstanding under the facility.

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The fee, expressed as a percentage of the line of credit facility, for available but unused credit capacity under the credit facility.

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- Definition

The cash outflow associated with the purchase of or advances to an equity method investments, which are investments in joint ventures and entities in which the entity has an equity ownership interest normally of 20 to 50 percent and exercises significant influence.

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- Definition

Amount of transactions with related party during the financial reporting period.

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- Definition

Expenses recognized resulting from transactions (excluding transactions that are eliminated in consolidated or combined financial statements) with related party.

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- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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- Definition

Percentage of the Variable Interest Entity's (VIE) voting interest owned by (or beneficial interest in) the reporting entity (directly or indirectly).

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Related Party Transactions (Details)		1 Months Ended		3 Months Ended		9 Months Ended
Related Party Transactions (Details)	Feb. 25, 2020 USD ($)	Aug. 31, 2020 USD ($)	Nov. 30, 2016 USD ($)	Sep. 30, 2021 USD ($) shares	Sep. 30, 2020 USD ($)	Sep. 30, 2021 USD ($) shares	Sep. 30, 2020 USD ($)	Dec. 31, 2020 USD ($)	Aug. 01, 2019 USD ($) ft²	Nov. 30, 2015 USD ($)	Apr. 30, 2013
Related Party Transaction [Line Items]
Credit line capacity				$ 103,771,000		$ 103,771,000
Amounts outstanding under line of credit				14,064,000		14,064,000		$ 22,954,000
Reimbursement paid to related party for travel				$ 0	$ 62,000	$ 43,000	$ 156,000
Detect Genomix \| Variable Interest Entity, Not Primary Beneficiary
Related Party Transaction [Line Items]
Additional investment in equity method investment		$ 245,000
Equity method investment, ownership percentage		49.00%
Pharmsynthez
Related Party Transaction [Line Items]
Equity method investment, ownership percentage				9.00%		9.00%					9.00%
Zebra
Related Party Transaction [Line Items]
Stock ownership percentage						29.00%
Zebra \| Variable Interest Entity, Not Primary Beneficiary
Related Party Transaction [Line Items]
Equity method investment, ownership percentage				29.00%		29.00%
Neovasc
Related Party Transaction [Line Items]
Equity method investment, ownership percentage				1.00%		1.00%
ChromaDex Corporation
Related Party Transaction [Line Items]
Ownership percentage				0.10%		0.10%
COCP
Related Party Transaction [Line Items]
Equity method investment, ownership percentage				3.00%		3.00%
NIMS
Related Party Transaction [Line Items]
Ownership percentage				1.00%		1.00%
Eloxx Pharmaceuticals
Related Party Transaction [Line Items]
Ownership percentage				2.00%		2.00%
BioCardia, Inc.
Related Party Transaction [Line Items]
Equity method investment, ownership percentage				1.00%		1.00%
Ownership percentage				1.00%		1.00%
InCellDx, Inc
Related Party Transaction [Line Items]
Equity method investment, ownership percentage				29.00%		29.00%
Frost Real Estate Holdings LLC
Related Party Transaction [Line Items]
Area of real estate property (in square feet) \| ft²									29,500
Lease payments per month in first year									$ 89,000
Lease payments per month in fifth year									$ 101,000
Federal Trade Commission Filing Fees \| Dr. Jan Hsiao
Related Party Transaction [Line Items]
Related party transaction amount		$ 125,000
Federal Trade Commission Filing Fees \| Dr. Frost
Related Party Transaction [Line Items]
Related party transaction amount		280,000
Shares Received Upon Closing of Xenetic Transaction \| Director
Related Party Transaction [Line Items]
Shares received upon closing of transaction (in shares) \| shares				31,240		31,240
Mednax Services, Inc. \| Detect Genomix \| Variable Interest Entity, Not Primary Beneficiary
Related Party Transaction [Line Items]
Additional investment in equity method investment		$ 255,000
Equity method investment, ownership percentage		51.00%
Museum of Science, Inc \| Dr Frost and Mr Pfenniger
Related Party Transaction [Line Items]
Related party future contribution			$ 1,000,000
Related party future contribution term			4 years
Line of Credit \| Unsecured Debt
Related Party Transaction [Line Items]
Credit line capacity	$ 100,000,000
Amounts outstanding under line of credit				$ 0		$ 0
Revolving Credit Facility \| New Credit Agreement \| Line of Credit
Related Party Transaction [Line Items]
Credit line capacity										$ 75,000,000
Commitment fee (as a percent)	0.25%