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Composition of Certain Financial Statement Captions - Changes in Goodwill (Details)
$ in Thousands
6 Months Ended
Jun. 30, 2019
USD ($)
Goodwill [Roll Forward]  
Beginning balance $ 700,193
Foreign exchange and other (351)
Ending balance 699,842
BioReference  
Goodwill [Roll Forward]  
Ending balance 401,800
Pharmaceutical | CURNA  
Goodwill [Roll Forward]  
Beginning balance 4,827
Foreign exchange and other 0
Ending balance 4,827
Pharmaceutical | EirGen  
Goodwill [Roll Forward]  
Beginning balance 85,245
Foreign exchange and other (551)
Ending balance 84,694
Pharmaceutical | FineTech  
Goodwill [Roll Forward]  
Beginning balance 0
Foreign exchange and other 0
Ending balance 0
Pharmaceutical | OPKO Chile  
Goodwill [Roll Forward]  
Beginning balance 4,614
Foreign exchange and other 112
Ending balance 4,726
Pharmaceutical | OPKO Biologics  
Goodwill [Roll Forward]  
Beginning balance 139,784
Foreign exchange and other 0
Ending balance 139,784
Pharmaceutical | OPKO Health Europe  
Goodwill [Roll Forward]  
Beginning balance 7,545
Foreign exchange and other (49)
Ending balance 7,496
Pharmaceutical | OPKO Renal  
Goodwill [Roll Forward]  
Beginning balance 2,069
Foreign exchange and other 0
Ending balance 2,069
Pharmaceutical | Transition Therapeutics  
Goodwill [Roll Forward]  
Beginning balance 3,323
Foreign exchange and other 137
Ending balance 3,460
Diagnostics | BioReference  
Goodwill [Roll Forward]  
Beginning balance 401,821
Foreign exchange and other 0
Ending balance 401,821
Diagnostics | OPKO Diagnostics  
Goodwill [Roll Forward]  
Beginning balance 17,977
Foreign exchange and other 0
Ending balance 17,977
Diagnostics | OPKO Lab  
Goodwill [Roll Forward]  
Beginning balance 32,988
Foreign exchange and other 0
Ending balance $ 32,988