Related Party Transactions - Textual (Details) (USD $)
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12 Months Ended |
3 Months Ended |
12 Months Ended |
1 Months Ended |
0 Months Ended |
12 Months Ended |
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Dec. 31, 2012
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Mar. 31, 2015
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Mar. 31, 2014
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Dec. 31, 2014
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Feb. 28, 2014
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Jan. 16, 2014
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Dec. 31, 2015
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Jan. 31, 2013
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Aug. 31, 2013
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Jul. 28, 2014
sqft
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Notes | Notes Due February 1, 2033 |
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Related Party Transaction [Line Items] |
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Debt face amount |
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$ 175,000,000.0us-gaap_DebtInstrumentFaceAmount / us-gaap_DebtInstrumentAxis = opk_NotesDueFebruary12033Member / us-gaap_LongtermDebtTypeAxis = us-gaap_ConvertibleNotesPayableMember |
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ARNO |
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Related Party Transaction [Line Items] |
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Warrants to purchase common shares |
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800,000us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights / us-gaap_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis = opk_ARNOMember |
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Ownership percentage |
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4.00%us-gaap_EquityMethodInvestmentOwnershipPercentage / us-gaap_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis = opk_ARNOMember |
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Zebra |
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Related Party Transaction [Line Items] |
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Ownership percentage |
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27.00%us-gaap_EquityMethodInvestmentOwnershipPercentage / us-gaap_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis = opk_ZebraMember |
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Sevion |
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Related Party Transaction [Line Items] |
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Warrants to purchase common shares |
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100,000us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights / us-gaap_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis = opk_SevionMember |
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Ownership percentage |
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4.00%us-gaap_EquityMethodInvestmentOwnershipPercentage / us-gaap_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis = opk_SevionMember |
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Chromadex Corporation |
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Related Party Transaction [Line Items] |
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Ownership percentage |
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2.00%us-gaap_EquityMethodInvestmentOwnershipPercentage / us-gaap_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis = opk_ChromadexCorporationMember |
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Biozone Pharmaceuticals Inc |
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Related Party Transaction [Line Items] |
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Invested in common shares |
1,700,000us-gaap_PaymentsToAcquireAvailableForSaleSecurities / us-gaap_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis = opk_BiozonePharmaceuticalsIncMember |
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Cocrystal |
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Related Party Transaction [Line Items] |
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Warrants to purchase common shares |
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1,000,000us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights / us-gaap_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis = opk_CocrystalMember |
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Ownership percentage |
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8.00%us-gaap_EquityMethodInvestmentOwnershipPercentage / us-gaap_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis = opk_CocrystalMember |
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Neovasc |
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Related Party Transaction [Line Items] |
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Warrants to purchase common shares |
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1,000,000us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights / us-gaap_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis = opk_NeovascMember |
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Ownership percentage |
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5.00%us-gaap_EquityMethodInvestmentOwnershipPercentage / us-gaap_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis = opk_NeovascMember |
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Dr Frost | OPKO Biologics |
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Related Party Transaction [Line Items] |
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Beneficially owned held by members |
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5.00%opk_OwnershipPercentageHeldByMembers / dei_LegalEntityAxis = opk_OPKOBiologicsMember / us-gaap_RelatedPartyTransactionsByRelatedPartyAxis = opk_DrFrostMember |
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Dr. Hsiao and Mr. Rubin | OPKO Biologics |
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Related Party Transaction [Line Items] |
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Beneficially owned held by members |
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5.00%opk_OwnershipPercentageHeldByMembers / dei_LegalEntityAxis = opk_OPKOBiologicsMember / us-gaap_RelatedPartyTransactionsByRelatedPartyAxis = opk_Dr.HsiaoandMr.RubinMember |
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Frost Gamma Investments Trust and Hsu Gamma Investment, L.P. | Notes | Notes Due February 1, 2033 |
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Related Party Transaction [Line Items] |
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Debt face amount |
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175,000,000us-gaap_DebtInstrumentFaceAmount / us-gaap_DebtInstrumentAxis = opk_NotesDueFebruary12033Member / us-gaap_LongtermDebtTypeAxis = us-gaap_ConvertibleNotesPayableMember / us-gaap_RelatedPartyTransactionsByRelatedPartyAxis = opk_FrostGammaInvestmentsTrustandHsuGammaInvestmentL.P.Member |
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Teva | FineTech |
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Related Party Transaction [Line Items] |
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Sale of API to TEVA |
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0us-gaap_RevenueFromRelatedParties / dei_LegalEntityAxis = opk_FineTechMember / us-gaap_RelatedPartyTransactionsByRelatedPartyAxis = opk_TevaPharmaceuticalIndustriesMember |
100,000us-gaap_RevenueFromRelatedParties / dei_LegalEntityAxis = opk_FineTechMember / us-gaap_RelatedPartyTransactionsByRelatedPartyAxis = opk_TevaPharmaceuticalIndustriesMember |
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Frost Real Estate Holdings LLC |
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Related Party Transaction [Line Items] |
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Area of real estate property (in square feet) |
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22,000us-gaap_AreaOfRealEstateProperty / us-gaap_RelatedPartyTransactionsByRelatedPartyAxis = opk_FrostRealEstateHoldingsLLCMember |
Operating Leases, Monthly Payments, Year One |
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57,000opk_OperatingLeasesMonthlyPaymentsYearOne / us-gaap_RelatedPartyTransactionsByRelatedPartyAxis = opk_FrostRealEstateHoldingsLLCMember |
Operating Leases, Monthly Payments, Year Five |
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65,000opk_OperatingLeasesMonthlyPaymentsYearFive / us-gaap_RelatedPartyTransactionsByRelatedPartyAxis = opk_FrostRealEstateHoldingsLLCMember |
Tenant Improvements, Offset Against Operating Lease in Next Twelve Months |
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216,000opk_TenantImprovementsOffsetAgainstOperatingLeaseinNextTwelveMonths / us-gaap_RelatedPartyTransactionsByRelatedPartyAxis = opk_FrostRealEstateHoldingsLLCMember |
Real Estate Holdings LLC |
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Related Party Transaction [Line Items] |
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Credit for tenant improvements |
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113,000us-gaap_TenantReimbursements / us-gaap_RelatedPartyTransactionsByRelatedPartyAxis = opk_RealEstateHoldingsLlcMember |
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FTC Filings | Dr Frost |
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Related Party Transaction [Line Items] |
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Payments for Filing Fees |
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280,000opk_PaymentsforFilingFees / us-gaap_RelatedPartyTransactionAxis = opk_FTCFilingsMember / us-gaap_RelatedPartyTransactionsByRelatedPartyAxis = opk_DrFrostMember |
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Equity Method Investee | Biozone |
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Related Party Transaction [Line Items] |
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Invested in common shares |
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500,000us-gaap_PaymentsToAcquireEquityMethodInvestments / us-gaap_RelatedPartyTransactionAxis = us-gaap_EquityMethodInvesteeMember / us-gaap_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis = opk_BiozoneMember |
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Private Placement Financing |
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2,750,000opk_PrivatePlacementFinancing / us-gaap_RelatedPartyTransactionAxis = us-gaap_EquityMethodInvesteeMember / us-gaap_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis = opk_BiozoneMember |
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Investment Owned, Balance, Shares |
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1,000,000us-gaap_InvestmentOwnedBalanceShares / us-gaap_RelatedPartyTransactionAxis = us-gaap_EquityMethodInvesteeMember / us-gaap_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis = opk_BiozoneMember |
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Warrants to purchase common shares |
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1,000,000us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights / us-gaap_RelatedPartyTransactionAxis = us-gaap_EquityMethodInvesteeMember / us-gaap_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis = opk_BiozoneMember |
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Warrants exercisable price (in USD per share) |
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$ 0.50us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1 / us-gaap_RelatedPartyTransactionAxis = us-gaap_EquityMethodInvesteeMember / us-gaap_ScheduleOfEquityMethodInvestmentEquityMethodInvesteeNameAxis = opk_BiozoneMember |
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Warrants duration |
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10 years |
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Reimbursement Of Travel Expense | Dr Frost |
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Related Party Transaction [Line Items] |
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Reimbursement paid to related party for travel |
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126,000us-gaap_RelatedPartyTransactionExpensesFromTransactionsWithRelatedParty / us-gaap_RelatedPartyTransactionAxis = opk_ReimbursementOfTravelExpenseMember / us-gaap_RelatedPartyTransactionsByRelatedPartyAxis = opk_DrFrostMember |
17,000us-gaap_RelatedPartyTransactionExpensesFromTransactionsWithRelatedParty / us-gaap_RelatedPartyTransactionAxis = opk_ReimbursementOfTravelExpenseMember / us-gaap_RelatedPartyTransactionsByRelatedPartyAxis = opk_DrFrostMember |
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Scenario, Forecast [Member] | Real Estate Holdings LLC |
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Related Party Transaction [Line Items] |
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Credit for tenant improvements |
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$ 103,000us-gaap_TenantReimbursements / us-gaap_RelatedPartyTransactionsByRelatedPartyAxis = opk_RealEstateHoldingsLlcMember / us-gaap_StatementScenarioAxis = us-gaap_ScenarioForecastMember |
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