Composition of Certain Financial Statement Captions (Details 1) (USD $) In Thousands, unless otherwise specified	12 Months Ended
	Dec. 31, 2014		Dec. 31, 2013		Dec. 31, 2012	Mar. 31, 2013
Fair values assigned to major intangible asset classes upon each acquisition
Goodwill	224,292	[1]	$ 226,373	[1]	$ 80,450
Technology
Fair values assigned to major intangible asset classes upon each acquisition
Weighted average amortization period	9 years
Customer relationships
Fair values assigned to major intangible asset classes upon each acquisition
Weighted average amortization period	6 years
Product registrations
Fair values assigned to major intangible asset classes upon each acquisition
Weighted average amortization period	9 years
Covenants not to compete
Fair values assigned to major intangible asset classes upon each acquisition
Weighted average amortization period	5 years
Tradename
Fair values assigned to major intangible asset classes upon each acquisition
Weighted average amortization period	4 years
Other
Fair values assigned to major intangible asset classes upon each acquisition
Weighted average amortization period	4 years
OPKO Chile
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	10,806	[2]
Goodwill	5,441	[2]
OPKO Chile | Customer relationships
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	3,945	[2]
OPKO Chile | Product registrations
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	5,829	[2]
OPKO Chile | Tradename
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	1,032	[2]
OPKO Mexico
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	345
Goodwill	21
OPKO Mexico | Customer relationships
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	121
OPKO Mexico | Product registrations
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	77
OPKO Mexico | Covenants not to compete
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	70
OPKO Mexico | Tradename
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	77
CURNA
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	10,290
Goodwill	4,827
CURNA | In-process research research and development
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	10,000
CURNA | Other
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	290
OPKO Diagnostics
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	44,400
Goodwill	17,977
OPKO Diagnostics | Technology
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	44,400
FineTech
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	18,800
Goodwill	11,623
FineTech | Technology
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	2,700
FineTech | Customer relationships
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	14,200
FineTech | Covenants not to compete
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	1,500
FineTech | Tradename
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	400
OPKO Health Europe
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	8,378
Goodwill	8,062
OPKO Health Europe | Technology
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	3,017
OPKO Health Europe | In-process research research and development
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	1,459
OPKO Health Europe | Customer relationships
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	436
OPKO Health Europe | Product registrations
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	2,930
OPKO Health Europe | Covenants not to compete
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	187
OPKO Health Europe | Tradename
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	349
OPKO Lab
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	14,030
Goodwill	29,629
OPKO Lab | Technology
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	1,370
OPKO Lab | Customer relationships
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	3,860
OPKO Lab | Covenants not to compete
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	6,900
OPKO Lab | Tradename
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	1,830
OPKO Lab | Other
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	70
SciVac
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	1,130
Goodwill	760
SciVac | Technology
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	1,090
SciVac | Customer relationships
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	40
OPKO Brazil
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	686
OPKO Brazil | Other
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	686
OPKO Renal
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	191,740
Goodwill	2,411					2,411
OPKO Renal | In-process research research and development
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	191,530
OPKO Renal | Other
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	210
OPKO Biologics
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	590,200
Goodwill	139,784
OPKO Biologics | In-process research research and development
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	590,200
OPKO Uruguay Ltda.
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	347
OPKO Uruguay Ltda. | Other
Fair values assigned to major intangible asset classes upon each acquisition
Total identified intangible assets	347

[1] As of December 31, 2014 and December 31, 2013, total assets include $7.6 million and $6.7 million, respectively, and total liabilities include $12.1 million and $10.4 million, respectively, related to SciVac, previously known as SciGen (I.L.) Ltd, a consolidated variable interest entity. SciVac’s consolidated assets are owned by SciVac and SciVac’s consolidated liabilities have no recourse against us. Refer to Note 4.

[2] Includes intangible assets and goodwill related to ALS acquisition.