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Acquisitions, Investments, and Licenses - Summary of Pro Forma Results (Details) (USD $)
In Thousands, except Per Share data, unless otherwise specified
12 Months Ended
Dec. 31, 2013
Dec. 31, 2012
Pro Forma Result of Combined Companies    
Revenues $ 96,530us-gaap_BusinessAcquisitionsProFormaRevenue $ 53,595us-gaap_BusinessAcquisitionsProFormaRevenue
Loss from continuing operations 0us-gaap_BusinessAcquisitionsProFormaIncomeLossFromContinuingOperationsBeforeChangesInAccountingAndExtraordinaryItemsNetOfTax (63,479)us-gaap_BusinessAcquisitionsProFormaIncomeLossFromContinuingOperationsBeforeChangesInAccountingAndExtraordinaryItemsNetOfTax
Net loss (147,546)us-gaap_BusinessAcquisitionsProFormaNetIncomeLoss (55,663)us-gaap_BusinessAcquisitionsProFormaNetIncomeLoss
Net loss attributable to common shareholders $ (145,027)opk_BusinessAcquisitionProFormaNetIncomeLossAvailabletoCommonStockholders $ (57,411)opk_BusinessAcquisitionProFormaNetIncomeLossAvailabletoCommonStockholders
Basic and diluted loss per share (in dollars per share) $ (0.37)opk_BusinessAcquisitionProFormaEarningsPerShareBasicandDiluted $ (0.15)opk_BusinessAcquisitionProFormaEarningsPerShareBasicandDiluted