The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACADIA PHARMACEUTICALS IN COM 004225108   3,739,599 179,702 SH   SOLE   179,702 0 0
AGIOS PHARMACEUTICALS INC COM 00847X104   593,520 24,000 SH   SOLE   24,000 0 0
AKERO THERAPEUTICS INC CO COM 00973Y108   935,174 18,489 SH   SOLE   18,489 0 0
ALNYLAM PHARMACEUTICALS I COM 02043Q107   6,517,280 36,800 SH   SOLE   36,800 0 0
AMGEN INC COM COM 031162100   21,297,363 79,246 SH   SOLE   79,246 0 0
AMICUS THERAPEUTICS INC C COM 03152W109   1,092,600 90,000 SH   SOLE   90,000 0 0
AMYLYX PHARMS. COM 03237H101   5,398,500 295,000 SH   SOLE   295,000 0 0
ARVINAS INC COM COM 04335A105   333,540 17,000 SH   SOLE   17,000 0 0
ASTRAZENECA PLC SPONSORED SPONSORED ADR 046353108   3,148,515 46,500 SH   SOLE   46,500 0 0
AURINIA PHARMACEUTICALS I COM 05156V102   8,074,513 1,040,530 SH   SOLE   1,040,530 0 0
AXSOME THERAPEUTICS INC. COM 05464T104   4,071,089 58,300 SH   SOLE   58,300 0 0
BEAM THERAPEUTICS INC COM COM 07373V105   564,705 23,500 SH   SOLE   23,500 0 0
BEIGENE LTD SPONSORED ADR Sponsored ADR 07725L102   2,281,555 12,700 SH   SOLE   12,700 0 0
BIOGEN INC COMMON STOCK COM 09062X103   10,333,812 40,200 SH   SOLE   40,200 0 0
BIOMARIN PHARMACEUTICAL I COM 09061G101   13,595,483 153,656 SH   SOLE   153,656 0 0
BLUEPRINT MEDICINES CORP COM 09627Y109   1,002,200 20,000 SH   SOLE   20,000 0 0
CELLDEX THERAPEUTICS INC COM NEW 15117B202   1,322,242 48,099 SH   SOLE   48,099 0 0
COGENT BIOSCIENCES COM 19240Q201   1,313,550 135,000 SH   SOLE   135,000 0 0
CRISPR THERAPEUTICS AG CO NAMEN AKT H17182108   2,858,940 63,000 SH   SOLE   63,000 0 0
CYTOKINETICS INC COMMON S COM NEW 23282W605   1,090,020 37,000 SH   SOLE   37,000 0 0
DENALI THERAPEUTICS INC C COM 24823R105   3,172,400 154,000 SH   SOLE   154,000 0 0
DYNE THERAPEUTICS INC COM COM 26818M108   1,231,494 137,751 SH   SOLE   137,751 0 0
ERASCA INC COM COM 29479A108   3,794,220 1,926,000 SH   SOLE   1,926,000 0 0
GENMAB -SP ADR SPONSORED ADS 372303206   1,561,575 44,300 SH   SOLE   44,300 0 0
GILEAD SCIENCES INC COMMO COM 375558103   17,507,121 233,584 SH   SOLE   233,584 0 0
GUARDANT HEALTH INC COM COM 40131M109   1,081,130 36,500 SH   SOLE   36,500 0 0
HALOZYME THERAPEUTICS INC COM 40637H109   2,376,040 62,200 SH   SOLE   62,200 0 0
Harmony Biosciences Holdi COM 413197104   10,306,165 314,500 SH   SOLE   314,500 0 0
ILLUMINA INC COM COM 452327109   6,932,640 50,500 SH   SOLE   50,500 0 0
I-MAB SPONSORED ADS SPONSORED ADS 44975P103   409,859 310,499 SH   SOLE   310,499 0 0
INCYTE CORP INC COM COM 45337C102   20,704,303 358,454 SH   SOLE   358,454 0 0
INSMED INC COM PAR $.01 COM 457669307   1,012,124 40,100 SH   SOLE   40,100 0 0
INTELLIA THERAPEUTICS INC COM 45826J105   757,920 24,000 SH   SOLE   24,000 0 0
INTRA-CELLULAR THERAPIES COM 46116X101   16,547,583 317,856 SH   SOLE   317,856 0 0
IONIS PHARMACEUTICALS INC COM 462222100   1,949,190 43,000 SH   SOLE   43,000 0 0
IOVANCE BIOTHERAPEUTICS I COM 462260100   2,024,750 445,000 SH   SOLE   445,000 0 0
JAZZ PHARMACEUTICALS PLC SHS USD G50871105   2,225,164 17,200 SH   SOLE   17,200 0 0
KARUNA THERAPEUTICS INC C COM 48576A100   5,157,245 30,500 SH   SOLE   30,500 0 0
KEZAR LIFE SCIENCES COM 49372L100   830,514 703,825 SH   SOLE   703,825 0 0
KRYSTAL BIOTECH INC COM COM 501147102   5,344,828 46,092 SH   SOLE   46,092 0 0
Legend Biotech Corp SPONSORED ADS 52490G102   2,551,320 38,000 SH   SOLE   38,000 0 0
MADRIGAL PHARMACEUTICALS COM 558868105   2,669,421 18,300 SH   SOLE   18,300 0 0
MARINUS PHARMACEUTICALS I COM NEW 56854Q200   2,337,400 290,000 SH   SOLE   290,000 0 0
MIRATI THERAPEUTICS INC C COM 60468T105   9,404,640 216,000 SH   SOLE   216,000 0 0
MIRUM PHARMACEUTICALS INC COM 604749101   2,128,950 67,500 SH   SOLE   67,500 0 0
NEUROCRINE BIOSCIENCES IN COM 64125C109   3,247,219 28,877 SH   SOLE   28,877 0 0
Novocure Ltd ORD SHS G6674U108   1,193,620 74,000 SH   SOLE   74,000 0 0
PROTAGONIST THERAPEUTICS COM 74366E102   331,932 19,900 SH   SOLE   19,900 0 0
PROTHENA CORP PLC USD0.01 COM G72800108   722,850 15,000 SH   SOLE   15,000 0 0
PTC THERAPEUTICS INC COM COM 69366J200   380,630 17,000 SH   SOLE   17,000 0 0
REGENERON PHARMACEUTICALS COM 75886F107   7,278,338 8,847 SH   SOLE   8,847 0 0
RELMADA THERAPEUTICS INC COM 75955J402   30,000 10,000 SH   SOLE   10,000 0 0
REVANCE THERAPEUTICS INC COM 761330109   3,308,800 288,726 SH   SOLE   288,726 0 0
ROCKET PHARMACEUTICALS IN COM 77313F106   3,193,320 156,000 SH   SOLE   156,000 0 0
SAREPTA THERAPEUTICS INC COM 803607100   3,234,972 26,700 SH   SOLE   26,700 0 0
SUPERNUS PHARMACEUTICALS COM 868459108   11,754,340 426,500 SH   SOLE   426,500 0 0
ULTRAGENYX PHARMACEUTICAL COM 90400D108   8,914,354 250,052 SH   SOLE   250,052 0 0
UNIQURE N.V. COM EUR0.05 SHS N90064101   8,330,465 1,241,500 SH   SOLE   1,241,500 0 0
UNITED THERAPEUTICS CORP COM 91307C102   7,657,755 33,959 SH   SOLE   33,959 0 0
VENTYX BIOSCIENCES INC CO COM 92332V107   520,650 15,000 SH   SOLE   15,000 0 0
VERA THERAPEUTICS CL A 92337R101   10,381,880 758,355 SH   SOLE   758,355 0 0
VERTEX PHARMACEUTICALS IN COM 92532F100   7,302,540 21,000 SH   SOLE   21,000 0 0
VIR BIOTECHNOLOGY INC COM COM 92764N102   439,920 47,000 SH   SOLE   47,000 0 0
XENON PHARMACEUTICALS INC COM 98420N105   3,121,980 91,500 SH   SOLE   91,500 0 0
ZAI LAB LTD ADR ADR 98887Q104   1,917,890 78,958 SH   SOLE   78,958 0 0