0000950123-23-010374.txt : 20231114 0000950123-23-010374.hdr.sgml : 20231114 20231114061605 ACCESSION NUMBER: 0000950123-23-010374 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20230930 FILED AS OF DATE: 20231114 DATE AS OF CHANGE: 20231114 EFFECTIVENESS DATE: 20231114 FILER: COMPANY DATA: COMPANY CONFORMED NAME: INTERNATIONAL BIOTECHNOLOGY TRUST PLC CENTRAL INDEX KEY: 0000942257 IRS NUMBER: 000000000 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-18673 FILM NUMBER: 231401412 BUSINESS ADDRESS: STREET 1: 6TH FLOOR, 65 GRESHAM STREET CITY: LONDON STATE: X0 ZIP: EC2V 7NQ BUSINESS PHONE: 44 (0) 20 7421 7070 MAIL ADDRESS: STREET 1: 6TH FLOOR, 65 GRESHAM STREET CITY: LONDON STATE: X0 ZIP: EC2V 7NQ 13F-HR 1 primary_doc.xml X0202 13F-HR LIVE 0000942257 XXXXXXXX 09-30-2023 09-30-2023 false INTERNATIONAL BIOTECHNOLOGY TRUST PLC

6th Floor, 65 Gresham Street London X0 EC2V 7NQ

13F HOLDINGS REPORT 028-18673 N James Costine 0044 2074217070 James Costine London X0 11-13-2023 0 65 296845651 false INFORMATION TABLE 2 28099.xml INFORMATION TABLE FOR FORM 13F ACADIA PHARMACEUTICALS IN COM 004225108 3739599 179702 SH SOLE 179702 0 0 AGIOS PHARMACEUTICALS INC COM 00847X104 593520 24000 SH SOLE 24000 0 0 AKERO THERAPEUTICS INC CO COM 00973Y108 935174 18489 SH SOLE 18489 0 0 ALNYLAM PHARMACEUTICALS I COM 02043Q107 6517280 36800 SH SOLE 36800 0 0 AMGEN INC COM COM 031162100 21297363 79246 SH SOLE 79246 0 0 AMICUS THERAPEUTICS INC C COM 03152W109 1092600 90000 SH SOLE 90000 0 0 AMYLYX PHARMS. COM 03237H101 5398500 295000 SH SOLE 295000 0 0 ARVINAS INC COM COM 04335A105 333540 17000 SH SOLE 17000 0 0 ASTRAZENECA PLC SPONSORED SPONSORED ADR 046353108 3148515 46500 SH SOLE 46500 0 0 AURINIA PHARMACEUTICALS I COM 05156V102 8074513 1040530 SH SOLE 1040530 0 0 AXSOME THERAPEUTICS INC. COM 05464T104 4071089 58300 SH SOLE 58300 0 0 BEAM THERAPEUTICS INC COM COM 07373V105 564705 23500 SH SOLE 23500 0 0 BEIGENE LTD SPONSORED ADR Sponsored ADR 07725L102 2281555 12700 SH SOLE 12700 0 0 BIOGEN INC COMMON STOCK COM 09062X103 10333812 40200 SH SOLE 40200 0 0 BIOMARIN PHARMACEUTICAL I COM 09061G101 13595483 153656 SH SOLE 153656 0 0 BLUEPRINT MEDICINES CORP COM 09627Y109 1002200 20000 SH SOLE 20000 0 0 CELLDEX THERAPEUTICS INC COM NEW 15117B202 1322242 48099 SH SOLE 48099 0 0 COGENT BIOSCIENCES COM 19240Q201 1313550 135000 SH SOLE 135000 0 0 CRISPR THERAPEUTICS AG CO NAMEN AKT H17182108 2858940 63000 SH SOLE 63000 0 0 CYTOKINETICS INC COMMON S COM NEW 23282W605 1090020 37000 SH SOLE 37000 0 0 DENALI THERAPEUTICS INC C COM 24823R105 3172400 154000 SH SOLE 154000 0 0 DYNE THERAPEUTICS INC COM COM 26818M108 1231494 137751 SH SOLE 137751 0 0 ERASCA INC COM COM 29479A108 3794220 1926000 SH SOLE 1926000 0 0 GENMAB -SP ADR SPONSORED ADS 372303206 1561575 44300 SH SOLE 44300 0 0 GILEAD SCIENCES INC COMMO COM 375558103 17507121 233584 SH SOLE 233584 0 0 GUARDANT HEALTH INC COM COM 40131M109 1081130 36500 SH SOLE 36500 0 0 HALOZYME THERAPEUTICS INC COM 40637H109 2376040 62200 SH SOLE 62200 0 0 Harmony Biosciences Holdi COM 413197104 10306165 314500 SH SOLE 314500 0 0 ILLUMINA INC COM COM 452327109 6932640 50500 SH SOLE 50500 0 0 I-MAB SPONSORED ADS SPONSORED ADS 44975P103 409859 310499 SH SOLE 310499 0 0 INCYTE CORP INC COM COM 45337C102 20704303 358454 SH SOLE 358454 0 0 INSMED INC COM PAR $.01 COM 457669307 1012124 40100 SH SOLE 40100 0 0 INTELLIA THERAPEUTICS INC COM 45826J105 757920 24000 SH SOLE 24000 0 0 INTRA-CELLULAR THERAPIES COM 46116X101 16547583 317856 SH SOLE 317856 0 0 IONIS PHARMACEUTICALS INC COM 462222100 1949190 43000 SH SOLE 43000 0 0 IOVANCE BIOTHERAPEUTICS I COM 462260100 2024750 445000 SH SOLE 445000 0 0 JAZZ PHARMACEUTICALS PLC SHS USD G50871105 2225164 17200 SH SOLE 17200 0 0 KARUNA THERAPEUTICS INC C COM 48576A100 5157245 30500 SH SOLE 30500 0 0 KEZAR LIFE SCIENCES COM 49372L100 830514 703825 SH SOLE 703825 0 0 KRYSTAL BIOTECH INC COM COM 501147102 5344828 46092 SH SOLE 46092 0 0 Legend Biotech Corp SPONSORED ADS 52490G102 2551320 38000 SH SOLE 38000 0 0 MADRIGAL PHARMACEUTICALS COM 558868105 2669421 18300 SH SOLE 18300 0 0 MARINUS PHARMACEUTICALS I COM NEW 56854Q200 2337400 290000 SH SOLE 290000 0 0 MIRATI THERAPEUTICS INC C COM 60468T105 9404640 216000 SH SOLE 216000 0 0 MIRUM PHARMACEUTICALS INC COM 604749101 2128950 67500 SH SOLE 67500 0 0 NEUROCRINE BIOSCIENCES IN COM 64125C109 3247219 28877 SH SOLE 28877 0 0 Novocure Ltd ORD SHS G6674U108 1193620 74000 SH SOLE 74000 0 0 PROTAGONIST THERAPEUTICS COM 74366E102 331932 19900 SH SOLE 19900 0 0 PROTHENA CORP PLC USD0.01 COM G72800108 722850 15000 SH SOLE 15000 0 0 PTC THERAPEUTICS INC COM COM 69366J200 380630 17000 SH SOLE 17000 0 0 REGENERON PHARMACEUTICALS COM 75886F107 7278338 8847 SH SOLE 8847 0 0 RELMADA THERAPEUTICS INC COM 75955J402 30000 10000 SH SOLE 10000 0 0 REVANCE THERAPEUTICS INC COM 761330109 3308800 288726 SH SOLE 288726 0 0 ROCKET PHARMACEUTICALS IN COM 77313F106 3193320 156000 SH SOLE 156000 0 0 SAREPTA THERAPEUTICS INC COM 803607100 3234972 26700 SH SOLE 26700 0 0 SUPERNUS PHARMACEUTICALS COM 868459108 11754340 426500 SH SOLE 426500 0 0 ULTRAGENYX PHARMACEUTICAL COM 90400D108 8914354 250052 SH SOLE 250052 0 0 UNIQURE N.V. COM EUR0.05 SHS N90064101 8330465 1241500 SH SOLE 1241500 0 0 UNITED THERAPEUTICS CORP COM 91307C102 7657755 33959 SH SOLE 33959 0 0 VENTYX BIOSCIENCES INC CO COM 92332V107 520650 15000 SH SOLE 15000 0 0 VERA THERAPEUTICS CL A 92337R101 10381880 758355 SH SOLE 758355 0 0 VERTEX PHARMACEUTICALS IN COM 92532F100 7302540 21000 SH SOLE 21000 0 0 VIR BIOTECHNOLOGY INC COM COM 92764N102 439920 47000 SH SOLE 47000 0 0 XENON PHARMACEUTICALS INC COM 98420N105 3121980 91500 SH SOLE 91500 0 0 ZAI LAB LTD ADR ADR 98887Q104 1917890 78958 SH SOLE 78958 0 0