The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACADIA PHARMACEUTICALS IN COM 004225108   1,590,000 100,000 SH   SOLE   100,000 0 0
ADICET BIO INC COM COM 007002108   1,379,995 154,708 SH   SOLE   154,708 0 0
ALBIREO PHARMA INC COM COM 01345P106   820,420 38,000 SH   SOLE   38,000 0 0
ALKERMES PLC SHS SHS G01767105   15,483,230 593,000 SH   SOLE   593,000 0 0
ALLOGENE THERAPEUTICS INC COM 019770106   314,000 50,000 SH   SOLE   50,000 0 0
ALNYLAM PHARMACEUTICALS I COM 02043Q107   9,018,160 38,000 SH   SOLE   38,000 0 0
AMGEN INC COM COM 031162100   4,265,225 16,246 SH   SOLE   16,246 0 0
APELLIS PHARMACEUTICALS I COM 03753U106   1,638,256 31,700 SH   SOLE   31,700 0 0
ARVINAS INC COM COM 04335A105   580,550 17,000 SH   SOLE   17,000 0 0
ASCENDIS PHARMA A/S SPONS Sponsored ADR 04351P101   3,588,270 29,400 SH   SOLE   29,400 0 0
ASTRAZENECA PLC SPONSORED SPONSORED ADR 046353108   4,406,350 65,000 SH   SOLE   65,000 0 0
AURINIA PHARMACEUTICALS I COM 05156V102   2,477,650 573,530 SH   SOLE   573,530 0 0
BEAM THERAPEUTICS INC COM COM 07373V105   919,085 23,500 SH   SOLE   23,500 0 0
BEIGENE LTD SPONSORED ADR Sponsored ADR 07725L102   3,452,116 15,700 SH   SOLE   15,700 0 0
BIOCRYST PHARMACEUTICALS COM 09058V103   653,790 57,000 SH   SOLE   57,000 0 0
BIOGEN INC COMMON STOCK COM 09062X103   5,923,520 21,400 SH   SOLE   21,400 0 0
BIOMARIN PHARMACEUTICAL I COM 09061G101   4,514,467 43,656 SH   SOLE   43,656 0 0
BLACK DIAMOND THERAPEUTIC COM 0920E3105   79,200 44,000 SH   SOLE   44,000 0 0
CARIBOU BIOSCIENCES INC C COM 142038108   1,619,562 257,892 SH   SOLE   257,892 0 0
CHINOOK THERAPEUTICS INC COM 16961L106   8,914,788 340,389 SH   SOLE   340,389 0 0
CONCERT PHARMACEUTICALS I COM 206022105   1,172,672 200,800 SH   SOLE   200,800 0 0
CRISPR THERAPEUTICS AG CO NAMEN AKT H17182108   1,390,230 34,200 SH   SOLE   34,200 0 0
DENALI THERAPEUTICS INC C COM 24823R105   1,056,020 38,000 SH   SOLE   38,000 0 0
DYNE THERAPEUTICS INC COM COM 26818M108   7,417,157 641,068 SH   SOLE   641,068 0 0
EXELIXIS INC COM COM 30161Q104   8,709,720 543,000 SH   SOLE   543,000 0 0
FATE THERAPEUTICS INC COM COM 31189P102   463,680 46,000 SH   SOLE   46,000 0 0
FULCRUM THERAPEUTICS INC COM 359616109   1,408,497 193,741 SH   SOLE   193,741 0 0
GILEAD SCIENCES INC COMMO COM 375558103   4,942,435 57,584 SH   SOLE   57,584 0 0
GUARDANT HEALTH INC COM COM 40131M109   2,024,165 74,500 SH   SOLE   74,500 0 0
Harmony Biosciences Holdi COM 413197104   14,560,725 264,500 SH   SOLE   264,500 0 0
HORIZON THERAPEUTICS PLC SHS G4617B105   35,828,179 314,973 SH   SOLE   314,973 0 0
HUTCHMED CHINA LIMITED SP SPONSORED ADS 44842L103   1,003,000 68,000 SH   SOLE   68,000 0 0
IDEAYA BIOSCIENCES INC CO COM 45166A102   1,980,530 109,000 SH   SOLE   109,000 0 0
ILLUMINA INC COM COM 452327109   9,396,720 46,500 SH   SOLE   46,500 0 0
I-MAB SPONSORED ADS SPONSORED ADS 44975P103   1,291,676 310,499 SH   SOLE   310,499 0 0
INCYTE CORP INC COM COM 45337C102   18,390,990 229,000 SH   SOLE   229,000 0 0
INSMED INC COM PAR $.01 COM 457669307   800,396 40,100 SH   SOLE   40,100 0 0
INTELLIA THERAPEUTICS INC COM 45826J105   836,640 24,000 SH   SOLE   24,000 0 0
INTRA-CELLULAR THERAPIES COM 46116X101   11,733,964 221,856 SH   SOLE   221,856 0 0
IOVANCE BIOTHERAPEUTICS I COM 462260100   357,280 56,000 SH   SOLE   56,000 0 0
IRONWOOD PHARMACEUTICALS COM 46333X108   743,400 60,000 SH   SOLE   60,000 0 0
JAZZ PHARMACEUTICALS PLC SHS USD G50871105   2,739,444 17,200 SH   SOLE   17,200 0 0
KRYSTAL BIOTECH INC COM COM 501147102   3,558,150 45,000 SH   SOLE   45,000 0 0
Legend Biotech Corp SPONSORED ADS 52490G102   1,894,300 38,000 SH   SOLE   38,000 0 0
MIRATI THERAPEUTICS INC C COM 60468T105   11,055,640 244,000 SH   SOLE   244,000 0 0
MIRUM PHARMACEUTICALS INC COM 604749101   1,312,875 67,500 SH   SOLE   67,500 0 0
NOVAVAX INC COM 670002401   1,360,775 132,500 SH   SOLE   132,500 0 0
Novocure Ltd ORD SHS G6674U108   2,344,000 32,000 SH   SOLE   32,000 0 0
PTC THERAPEUTICS INC COM COM 69366J200   5,493,600 144,000 SH   SOLE   144,000 0 0
REGENERON PHARMACEUTICALS COM 75886F107   8,080,128 11,200 SH   SOLE   11,200 0 0
RELMADA THERAPEUTICS INC COM 75955J402   34,900 10,000 SH   SOLE   10,000 0 0
REVANCE THERAPEUTICS INC COM 761330109   2,214,000 120,000 SH   SOLE   120,000 0 0
ROCKET PHARMACEUTICALS IN COM 77313F106   1,231,020 63,000 SH   SOLE   63,000 0 0
SANOFI SPONSORED ADR 80105N105   6,942,530 143,500 SH   SOLE   143,500 0 0
SEAGEN INC COM COM 81181C104   21,356,700 166,200 SH   SOLE   166,200 0 0
SUPERNUS PHARMACEUTICALS COM 868459108   13,671,775 383,500 SH   SOLE   383,500 0 0
TRAVERE THERAPEUTICS INC COM 89422G107   7,963,189 379,019 SH   SOLE   379,019 0 0
ULTRAGENYX PHARMACEUTICAL COM 90400D108   8,060,348 174,052 SH   SOLE   174,052 0 0
UNIQURE N.V. COM EUR0.05 SHS N90064101   14,297,160 631,500 SH   SOLE   631,500 0 0
UNITED THERAPEUTICS CORP COM 91307C102   4,171,200 15,000 SH   SOLE   15,000 0 0
VERA THERAPEUTICS CL A 92337R101   5,428,260 281,257 SH   SOLE   281,257 0 0
XENON PHARMACEUTICALS INC COM 98420N105   1,003,425 25,500 SH   SOLE   25,500 0 0
ZAI LAB LTD ADR ADR 98887Q104   2,423,221 78,958 SH   SOLE   78,958 0 0