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Collaboration Agreements And Business Development Activities - Research Collaborations and In-Licensing Arrangements (Details) - USD ($)
$ in Thousands
1 Months Ended 12 Months Ended
Dec. 31, 2021
May 31, 2021
Dec. 31, 2021
Jan. 01, 2021
Jan. 03, 2020
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Research and development     $ 693,716 $ 547,851 $ 336,964
Collaborative Agreement With Gama Mabs Pharma S A          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Payments to acquire assets   $ 10,000      
Payment upon closing of transaction   4,000      
Asset acquisition, maximum aggregate development milestone payments   42,000      
Asset acquisition, maximum aggregate regulatory milestone payments   $ 22,500      
Research Collaborations, In-Licensing Arrangements and Other Business Development Activities          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Potential future development milestone payments $ 254,300   254,300    
Potential regulatory milestone payments 426,500   426,500    
Collaborative arrangement, rights and obligations, maximum aggregate commercial milestone payments 1,911,500   1,911,500    
Research and development     $ 176,100 $ 96,400 $ 47,700
Collaboration Agreement With Iconic Therapeutics Inc          
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]          
Collaboration agreement, final payment 55,000        
Research and development $ 55,000