<SEC-DOCUMENT>0001047469-16-012210-index.html : 20160414
<SEC-HEADER>0001047469-16-012210.hdr.sgml : 20160414
<ACCEPTANCE-DATETIME>20160414143317
ACCESSION NUMBER:		0001047469-16-012210
CONFORMED SUBMISSION TYPE:	S-4/A
PUBLIC DOCUMENT COUNT:		13
FILED AS OF DATE:		20160414
DATE AS OF CHANGE:		20160414

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Shire plc
		CENTRAL INDEX KEY:			0000936402
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-4/A
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-209648
		FILM NUMBER:		161571408

	BUSINESS ADDRESS:	
		STREET 1:		HAMPSHIRE INTL BUSINESS PARK
		STREET 2:		CHINEHAM BASINGSTOKE
		CITY:			HAMPSHIRE ENGLAND RG
		STATE:			X0
		ZIP:			RG24 8EP
		BUSINESS PHONE:		441256894000

	MAIL ADDRESS:	
		STREET 1:		HAMPSHIRE INTL BUSINESS PARK
		STREET 2:		CHINEHAM BASINGSTOKE
		CITY:			HAMPSHIRE ENGLAND RG
		STATE:			X0
		ZIP:			RG24 8EP

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Shire Ltd.
		DATE OF NAME CHANGE:	20080523

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Shire plc
		DATE OF NAME CHANGE:	20051125

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	SHIRE PHARMACEUTICALS GROUP PLC
		DATE OF NAME CHANGE:	19980302
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Document 1 - file: a2228253zs-4a.htm

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<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>2
<FILENAME>a2228253zex-5_1.htm
<DESCRIPTION>EX-5.1
<TEXT>
Document 2 - file: a2228253zex-5_1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.1
<SEQUENCE>3
<FILENAME>a2228253zex-23_1.htm
<DESCRIPTION>EX-23.1
<TEXT>
Document 3 - file: a2228253zex-23_1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.2
<SEQUENCE>4
<FILENAME>a2228253zex-23_2.htm
<DESCRIPTION>EX-23.2
<TEXT>
Document 4 - file: a2228253zex-23_2.htm

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<TYPE>EX-23.3
<SEQUENCE>5
<FILENAME>a2228253zex-23_3.htm
<DESCRIPTION>EX-23.3
<TEXT>
Document 5 - file: a2228253zex-23_3.htm

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<DOCUMENT>
<TYPE>EX-23.4
<SEQUENCE>6
<FILENAME>a2228253zex-23_4.htm
<DESCRIPTION>EX-23.4
<TEXT>
Document 6 - file: a2228253zex-23_4.htm

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<DOCUMENT>
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<SEQUENCE>7
<FILENAME>a2228253zex-99_2.htm
<DESCRIPTION>EX-99.2
<TEXT>
Document 7 - file: a2228253zex-99_2.htm

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<FILENAME>a2228253zex-99_3.htm
<DESCRIPTION>EX-99.3
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Document 8 - file: a2228253zex-99_3.htm

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<SEQUENCE>9
<FILENAME>a2228253zex-99_4.htm
<DESCRIPTION>EX-99.4
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Document 9 - file: a2228253zex-99_4.htm

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Document 10 - file: g329073.jpg

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Document 11 - file: g644439.jpg

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Document 12 - file: g29292msi001.gif

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Document 13 - file: g29292msi002.gif

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