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Related parties (Details) - ArmaGen
$ in Millions
9 Months Ended
Sep. 30, 2015
USD ($)
Related Party Transaction [Line Items]  
Amount paid for an equity stake and the license to develop and commercialize AGT-182 $ 2.5
Share of R&D credit recorded within R&D expense 7.2
Related parties, acrrued liabilities $ 0.7
Percentage of equity stake 21.00%