<SEC-DOCUMENT>0000950103-14-007323-index.html : 20141022
<SEC-HEADER>0000950103-14-007323.hdr.sgml : 20141022
<ACCEPTANCE-DATETIME>20141022082101
ACCESSION NUMBER:		0000950103-14-007323
CONFORMED SUBMISSION TYPE:	8-K
PUBLIC DOCUMENT COUNT:		6
CONFORMED PERIOD OF REPORT:	20141020
ITEM INFORMATION:		Entry into a Material Definitive Agreement
ITEM INFORMATION:		Termination of a Material Definitive Agreement
ITEM INFORMATION:		Financial Statements and Exhibits
FILED AS OF DATE:		20141022
DATE AS OF CHANGE:		20141022

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Shire plc
		CENTRAL INDEX KEY:			0000936402
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		8-K
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-29630
		FILM NUMBER:		141166855

	BUSINESS ADDRESS:	
		STREET 1:		HAMPSHIRE INTL BUSINESS PARK
		STREET 2:		CHINEHAM BASINGSTOKE
		CITY:			HAMPSHIRE ENGLAND RG
		STATE:			X0
		ZIP:			R924 8EP
		BUSINESS PHONE:		441256894000

	MAIL ADDRESS:	
		STREET 1:		HAMPSHIRE INTL BUSINESS PARK
		STREET 2:		CHINEHAM BASINGSTOKE
		CITY:			HAMPSHIRE ENGLAND RG
		STATE:			X0
		ZIP:			R924 8EP

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Shire Ltd.
		DATE OF NAME CHANGE:	20080523

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Shire plc
		DATE OF NAME CHANGE:	20051125

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	SHIRE PHARMACEUTICALS GROUP PLC
		DATE OF NAME CHANGE:	19980302
</SEC-HEADER>
<DOCUMENT>
<TYPE>8-K
<SEQUENCE>1
<FILENAME>dp50363_8k.htm
<DESCRIPTION>FORM 8-K
<TEXT>
Document 1 - file: dp50363_8k.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-2.1
<SEQUENCE>2
<FILENAME>dp50363_ex0201.htm
<DESCRIPTION>EXHIBIT 2.1
<TEXT>
Document 2 - file: dp50363_ex0201.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.1
<SEQUENCE>3
<FILENAME>dp50363_ex9901.htm
<DESCRIPTION>EXHIBIT 99.1
<TEXT>
Document 3 - file: dp50363_ex9901.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>4
<FILENAME>p01.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 4 - file: p01.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>5
<FILENAME>signature1.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 5 - file: signature1.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>6
<FILENAME>signature2.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 6 - file: signature2.jpg

</DOCUMENT>
</SEC-DOCUMENT>