Consolidated Statements of Income (USD $) In Millions, except Per Share data, unless otherwise specified	12 Months Ended
	Dec. 31, 2011		Dec. 31, 2010		Dec. 31, 2009
Revenues:
Product sales	$ 3,950.2		$ 3,128.2		$ 2,693.7
Royalties	283.5		328.1		292.5
Other revenues	29.7		14.8		21.5
Total revenues	4,263.4		3,471.1		3,007.7
Costs and expenses:
Cost of product sales	588.1	[1],[2]	463.4	[1],[3]	388.0	[1],[4]
Research and development	770.7	[1],[2]	661.5	[1],[3]	639.9	[1],[4]
Selling, general and administrative	1,751.4	[1],[2]	1,526.3	[1],[3]	1,342.6	[1],[4]
Loss/(gain) on sale of product rights	6.0		(16.5)		(6.3)
Reorganization costs	24.3		34.3		12.7
Integration and acquisition costs	13.7		8.0		10.6
Total operating expenses	3,154.2		2,677.0		2,387.5
Operating income	1,109.2		794.1		620.2
Interest income	1.9		2.4		1.9
Interest expense	(39.1)		(35.1)		(39.8)
Other income, net	18.1		7.9		60.7
Total other (expense)/income, net	(19.1)		(24.8)		22.8
Income from continuing operations before income taxes and equity in earnings/(losses) of equity method investees	1,090.1		769.3		643.0
Income taxes	(227.6)	[5]	(182.7)	[5]	(138.5)	[5]
Equity in earnings/(losses) of equity method investees, net of taxes	2.5		1.4		(0.7)
Income from continuing operations, net of taxes	865.0		588.0		503.8
Loss from discontinued operations (net of income tax expense of $nil in all periods)	0		0		(12.4)
Net income	865.0		588.0		491.4
Add: Net loss attributable to the noncontrolling interest in subsidiaries	0		0		0.2
Net income attributable to Shire plc	865.0		588.0		491.6
Earning per ordinary share - basic
Earnings from continuing operations attributable to Shire plc shareholders	$ 1.569		$ 1.077		$ 0.932
Loss from discontinued operations attributable to Shire plc shareholders	$ 0.000		$ 0.000		$ (0.023)
Earnings per ordinary share - basic	$ 1.569		$ 1.077		$ 0.909
Earnings per ordinary share - diluted
Earnings from continuing operations attributable to Shire plc shareholders	$ 1.509		$ 1.053		$ 0.919
Loss from discontinued operations attributable to Shire plc shareholders	$ 0.000		$ 0.000		$ (0.022)
Earnings per ordinary share - diluted	$ 1.509		$ 1.053		$ 0.897
Weighted average number of shares:
Basic	551.1		546.2		540.7
Diluted	595.4		590.3		548.0
Amounts attributable to Shire plc
Income from continuing operations, net of taxes	865.0		588.0		504.0
Loss from discontinued operations, net of taxes	0		0		(12.4)
Net income attributable to Shire plc	$ 865.0		$ 588.0		$ 491.6

[1] Cost of product sales includes amortization of intangible assets relating to favorable manufacturing contracts of $1.7 million for the year to December 31, 2011 (2010: $1.7 million; 2009: $1.7 million). Research and development costs include intangible asset impairment charges of $16.0 million for the year to December 31, 2011 (2010: $nil; 2009: $nil). Selling, general and administrative costs include amortization and impairment charges of intangible assets relating to intellectual property rights acquired of $165.0 million including impairment losses of $nil for the year to December 31, 2011 (2010: $176.2 million, including impairment losses of $42.7 million; 2009: $136.9 million, including impairment losses of $nil).

[2] Depreciation from manufacturing plants ($39.8 million) and amortization of favorable manufacturing contracts ($1.7 million) is included in Cost of product sales; depreciation of research and development assets ($25.2 million) and impairment of IPR&D intangible assets in the SP reporting segment ($16.0 million) is included in Research and development; and all other depreciation and amortization ($228.1 million) is included in Selling, general and administrative.

[3] Depreciation from manufacturing plants ($38.1 million) and amortization of favorable manufacturing contracts ($1.7 million) is included in Cost of product sales; depreciation of research and development assets ($19.0 million) is included in Research and development; and all other depreciation, amortization and impairment ($238.3 million) is included in Selling, general and administrative.

[4] Depreciation from manufacturing plants ($21.8 million) and amortization of favorable manufacturing contracts ($1.7 million) is included in Cost of product sales; depreciation of research and development assets ($15.5 million) is included in Research and development; and all other depreciation and amortization ($204.7 million) is included in Selling, general and administrative.

[5] Total income taxes relate solely to continuing operations as there is no tax provision/(benefit) relating to discontinued operations for the years to December 31, 2011, 2010 or 2009.