Shire Pharmaceuticals Group plc
Hampshire International Business Park,
Chineham, Basingstoke RG24 8EP UK
Tel +44 1256 894000 Fax +44 1256 894708
http://www.shire.com

Shire to Present at the Morgan Stanley Pharmaceutical CEOs Unplugged Conference

Basingstoke, UK and Philadelphia, US – 5 January 2005 – Shire Pharmaceuticals Group plc (LSE: SHP, NASDAQ: SHPGY, TSX: SHQ) announces that Mr Matthew Emmens, Chief Executive Officer will be presenting at the Morgan Stanley Pharmaceutical CEOs Unplugged Conference January 6, 2005 in New York - at 2:15 pm Eastern Time (7:15 pm GMT).

Investors may access a live audio webcast of the presentation at www.shire.com.

For further information please contact:
Investor Relations
Souheil Salah	+	44 1256 894 160

Notes to editors

Shire Pharmaceuticals Group plc

Shire Pharmaceuticals Group plc (Shire) is a global specialty pharmaceutical company with a strategic focus on meeting the needs of the specialist physician and currently focuses on developing projects and marketing products in the areas of central nervous system (CNS), gastrointestinal (GI), and renal diseases. Shire has operations in the world’s key pharmaceutical markets (US, Canada, UK, France, Italy, Spain and Germany) as well as a specialist drug delivery unit in the US.

For further information on Shire, please visit the Company’s website: www.shire.com.