EXHIBIT 32


The certification set forth below is being submitted in connection with the
Annual Report of the Company on Form 10-K for the year ended December 31, 2003
(the Report) for the purpose of complying with Rule 13a-14(b) or Rule 15d-14(b)
of the Securities Exchange Act of 1934 (the "Exchange Act") and Section 1350 of
Chapter 63 of Title 18 of the United States Code.

Matthew Emmens, the Chief Executive Officer and Angus Russell, the Chief
Financial Officer of Shire Pharmaceuticals Group plc (the Company), each
certifies that, to the best of his knowledge:

1.   the Report fully complies with the requirements of Section 13(a) or 15(d)
     of the Exchange Act; and

2.   the information contained in the Report fairly presents, in all material
     respects, the financial condition and results of operations of the Company.


Dated:  March 10, 2004                    /s/  Matthew Emmens
                                          -----------------------
                                          Matthew Emmens
                                          Chief Executive Officer

                                          /s/  Angus Russell
                                          -----------------------
                                          Angus Russell
                                          Chief Financial Officer