<SEC-DOCUMENT>0000936402-18-000109-index.html : 20181127
<SEC-HEADER>0000936402-18-000109.hdr.sgml : 20181127
<ACCEPTANCE-DATETIME>20181127111209
ACCESSION NUMBER:		0000936402-18-000109
CONFORMED SUBMISSION TYPE:	8-K
PUBLIC DOCUMENT COUNT:		7
CONFORMED PERIOD OF REPORT:	20181122
ITEM INFORMATION:		Other Events
ITEM INFORMATION:		Financial Statements and Exhibits
FILED AS OF DATE:		20181127
DATE AS OF CHANGE:		20181127

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			Shire plc
		CENTRAL INDEX KEY:			0000936402
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				000000000
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		8-K
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	001-37896
		FILM NUMBER:		181202377

	BUSINESS ADDRESS:	
		STREET 1:		BLOCK 2, MIESIAN PLAZA
		STREET 2:		50-58 BAGGOT STREET LOWER
		CITY:			DUBLIN 2
		STATE:			L2
		ZIP:			D02 HW68
		BUSINESS PHONE:		353-1-609-6000

	MAIL ADDRESS:	
		STREET 1:		BLOCK 2, MIESIAN PLAZA
		STREET 2:		50-58 BAGGOT STREET LOWER
		CITY:			DUBLIN 2
		STATE:			L2
		ZIP:			D02 HW68

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Shire Ltd.
		DATE OF NAME CHANGE:	20080523

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	Shire plc
		DATE OF NAME CHANGE:	20051125

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	SHIRE PHARMACEUTICALS GROUP PLC
		DATE OF NAME CHANGE:	19980302
</SEC-HEADER>
<DOCUMENT>
<TYPE>8-K
<SEQUENCE>1
<FILENAME>a8-kxnovember272018file.htm
<DESCRIPTION>8-K
<TEXT>
Document 1 - file: a8-kxnovember272018file.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.1
<SEQUENCE>2
<FILENAME>november222018-rule29xexhi.htm
<DESCRIPTION>EXHIBIT 99.1
<TEXT>
Document 2 - file: november222018-rule29xexhi.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.2
<SEQUENCE>3
<FILENAME>november232018-rule29xexhi.htm
<DESCRIPTION>EXHIBIT 99.2
<TEXT>
Document 3 - file: november232018-rule29xexhi.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.3
<SEQUENCE>4
<FILENAME>november232018-blsmrxexhib.htm
<DESCRIPTION>EXHIBIT 99.3
<TEXT>
Document 4 - file: november232018-blsmrxexhib.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.4
<SEQUENCE>5
<FILENAME>november262018-frmddxexhi.htm
<DESCRIPTION>EXHIBIT 99.4
<TEXT>
Document 5 - file: november262018-frmddxexhi.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-99.5
<SEQUENCE>6
<FILENAME>november272018-rule29xexhi.htm
<DESCRIPTION>EXHIBIT 99.5
<TEXT>
Document 6 - file: november272018-rule29xexhi.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>7
<FILENAME>shirelogobluergba67.jpg
<DESCRIPTION>GRAPHIC
<TEXT>
Document 7 - file: shirelogobluergba67.jpg

</DOCUMENT>
</SEC-DOCUMENT>