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Commitments and Contingencies (Narrative) (Details) - USD ($)
$ in Millions
3 Months Ended 6 Months Ended
Jun. 30, 2018
Jun. 30, 2017
Jun. 30, 2018
Jun. 30, 2017
Dec. 31, 2017
Commitments and Contingencies Disclosure [Abstract]          
Lease and rental expense $ 35.6 $ 42.4 $ 85.1 $ 85.0  
Irrevocable standby letters of credit and guarantees 229.3   229.3   $ 224.8
Clinical Testing          
Other Commitments [Line Items]          
Commitment amount 1,593.6   1,593.6   1,409.9
Contract Manufacturing          
Other Commitments [Line Items]          
Commitment amount 1,080.2   1,080.2   467.2
Commitments expected to be paid in next year 303.5   303.5    
Other Purchasing Commitment          
Other Commitments [Line Items]          
Commitment amount 1,563.9   1,563.9   1,692.5
Commitments expected to be paid in next year 1,045.1   1,045.1    
Investment Commitment          
Other Commitments [Line Items]          
Commitment amount 49.4   49.4   48.9
Capital Commitment          
Other Commitments [Line Items]          
Commitment amount $ 409.3   $ 409.3   $ 328.2