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Commitments and Contingencies (Narrative) (Details) - USD ($)
$ in Millions
3 Months Ended
Mar. 31, 2018
Mar. 31, 2017
Dec. 31, 2017
Commitments and Contingencies Disclosure [Abstract]      
Lease and rental expense $ 47.6 $ 42.6  
Irrevocable standby letters of credit and guarantees 223.0   $ 224.8
Clinical Testing      
Other Commitments [Line Items]      
Commitment amount 1,420.6   1,409.9
Contract Manufacturing      
Other Commitments [Line Items]      
Commitment amount 330.0   467.2
Commitments expected to be paid in next year 227.1    
Other Purchasing Commitment      
Other Commitments [Line Items]      
Commitment amount 1,521.8   1,692.5
Commitments expected to be paid in next year 1,169.0    
Investment Commitment      
Other Commitments [Line Items]      
Commitment amount 54.7   48.9
Capital Commitment      
Other Commitments [Line Items]      
Commitment amount $ 405.2   $ 328.2