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Summary of Significant Accounting Policies (Effects of Adoption of Topic 606 - Unaudited Consolidated Statements of Operations) (Details) - USD ($)
$ / shares in Units, $ in Millions
3 Months Ended
Mar. 31, 2018
Mar. 31, 2017
Revenue, Initial Application Period Cumulative Effect Transition [Line Items]    
Product sales $ 3,637.1 $ 3,412.3
Royalties and other revenues 128.6 160.0
Net income $ 550.6 $ 375.0
Net income per share applicable to common shareholders - basic (in usd per share) $ 0.61 $ 0.41
Net income per share applicable to common shareholders - diluted (in usd per share) $ 0.60 $ 0.41
Before Adoption of Topic 606 | ASU 2014-09    
Revenue, Initial Application Period Cumulative Effect Transition [Line Items]    
Product sales $ 3,642.5  
Royalties and other revenues 151.4  
Net income $ 572.4  
Net income per share applicable to common shareholders - basic (in usd per share) $ 0.63  
Net income per share applicable to common shareholders - diluted (in usd per share) $ 0.63  
Effect of change | ASU 2014-09    
Revenue, Initial Application Period Cumulative Effect Transition [Line Items]    
Product sales $ (5.4)  
Royalties and other revenues (22.8)  
Net income $ (21.8)  
Net income per share applicable to common shareholders - basic (in usd per share) $ (0.02)  
Net income per share applicable to common shareholders - diluted (in usd per share) $ (0.03)