Consolidated Statements of Operations - USD ($) shares in Millions, $ in Millions	3 Months Ended		9 Months Ended
	Sep. 30, 2016	Sep. 30, 2015	Sep. 30, 2016	Sep. 30, 2015
Revenues:
Product sales	$ 3,315.4	$ 1,576.8	$ 7,264.8	$ 4,476.2
Royalties and other revenues	136.7	78.2	325.7	224.8
Total revenues	3,452.1	1,655.0	7,590.5	4,701.0
Costs and expenses:
Cost of sales	1,736.2	262.7	2,762.9	718.5
Research and development	511.1	241.2	1,023.0	1,210.8
Selling, general and administrative	875.6	442.3	2,025.8	1,356.6
Amortization of acquired intangibles	354.9	132.7	702.5	352.3
Integration and acquisition costs	284.5	89.9	738.6	(46.8)
Reorganization costs	101.4	31.1	115.7	59.6
Gain on sale of product rights	(5.7)	(0.7)	(12.2)	(13.0)
Total operating expenses	3,858.0	1,199.2	7,356.3	3,638.0
Operating (loss)/income from continuing operations	(405.9)	455.8	234.2	1,063.0
Interest income	9.3	0.8	11.9	3.4
Interest expense	(186.9)	(10.7)	(318.8)	(31.6)
Other (expense)/income, net	(13.7)	9.6	(16.2)	11.9
Total other expense, net	(191.3)	(0.3)	(323.1)	(16.3)
(Loss)/income from continuing operations before income taxes and equity in losses of equity method investees	(597.2)	455.5	(88.9)	1,046.7
Income tax benefit	229.6	22.3	218.4	9.0
Equity in losses of equity method investees, net of taxes	(0.9)	(0.7)	(1.9)	(1.6)
(Loss)/income from continuing operations, net of taxes	(368.5)	477.1	127.6	1,054.1
Loss from discontinued operations, net of taxes	(18.3)	(24.3)	(257.5)	(31.3)
Net (loss)/income	$ (386.8)	$ 452.8	$ (129.9)	$ 1,022.8
(Loss)/earnings per ordinary share - basic
(Loss)/earnings from continuing operations (in usd per share)	$ (0.41)	$ 0.81	$ 0.18	$ 1.79
Loss from discontinued operations (in usd per share)	(0.02)	(0.04)	(0.36)	(0.06)
(Loss)/earnings per ordinary share - basic (in usd per share)	(0.43)	0.77	(0.18)	1.73
(Loss)/earnings per ordinary share - diluted
(Loss)/earnings from continuing operations (in usd per share)	(0.41)	0.80	0.18	1.78
Loss from discontinued operations (in usd per share)	(0.02)	(0.04)	(0.36)	(0.06)
(Loss)/earnings per ordinary share - diluted (in usd per share)	(0.43)	0.76	(0.18)	1.72
Cash dividends declared and paid per ordinary share (in usd per share)	$ 0	$ 0	$ 0.22	$ 0.19
Weighted average number of ordinary shares:
Basic (in shares)	900.2	590.9	725.5	590.2
Diluted (in shares)	900.2	593.4	725.5	593.2