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Taxation
9 Months Ended
Sep. 30, 2016
Income Tax Disclosure [Abstract]  
Taxation
Taxation 
For the three and nine months ended September 30, 2016, the effective tax rate on income from continuing operations was 38% (2015: -5%) and 246% (2015: -1%), respectively.
The effective tax rate for the three and nine months ended September 30, 2016 is affected by the combined impact of the relative quantum of the profit before tax for the period by jurisdiction and of the reversal of deferred tax liabilities from the Baxalta acquisition (including in higher tax territories such as the U.S.) of inventory and intangible assets amortization as well as significant acquisition and integration costs.
The effective tax rate for the three and nine months ended September 30, 2015 was negative primarily due to the release of certain valuation allowances, the effect of the finalization of various tax returns and the re-measurement of uncertain tax positions relating to ongoing tax audits all recognized during the third quarter of 2015.
The Company has historically calculated the provision for income taxes during interim reporting periods by applying an estimate of the annual effective tax rate for the full year to ordinary income or loss for the reporting period. For the three and nine months ended September 30, 2016, the impact of certain items arising from the Baxalta acquisition has caused significant variations in the estimated effective tax rate. As a result, the Company has applied a permitted exception to the general rule by including the actual income tax effect of certain portions of its business discretely when calculating the provision for income taxes for the three and nine months ended September 30, 2016.